Background: In recent studies, preoperative administration of gabapentin appears to play a role in postoperative pain control. However its use in children is still need further researches. So we aimed to evaluate the effect of gabapentin on management of postoperative orthopedic pediatric pain and consumption of analgesia.
Background: The requirement for cardiac output (CO) measurements typically restricts the widely used passive leg raising (PLR) test for a set of patients because they need costly or intrusive hemodynamic surveillance equipment. This trial aimed to evaluate the role of end-tidal CO2 pressure (EtCO2) monitoring in the prediction of the fluid responsiveness in connection to stroke volume variation (SVV) observed in unstable hemodynamic patients in electrical cardiometry (EC).
Methods: This prospective observational study was carried out on 60 cases aged 18 years or above with hypotension and mechanically ventilated patients in critical care. Patients were classified into two groups according to the SVV:a) Responder group (SVV≥10%) and b) non-responder group. All patients were mechanically ventilated and received sedation and muscle relaxation with no spontaneous respiratory effort.
Results: EtCO2 was significantly increased in responder group than non-responder group at the end (P value = 0.002). SVV was significantly higher in responder group than non-responder group at the baseline (P <0.001). There was a significant negative correlation between SVV and EtCo2 (r = -0.456, P <0.001) and a significant positive correlation between cardiac index and EtCO2 (r = -0.456, P = 0.005). Ä EtCO2 can predict fluid responsiveness significantly (P <0.001) at cut-off > 3 mmHg with 81.4% sensitivity, 88.24% specificity.
Conclusion: EtCO2 existed as a simple, inexpensive, and non-invasive alternative for the CO in the evaluation of various shock conditions. Ä EtCO2 can also predict fluid responsiveness significantly (P <0.001) at cut-off > 3 mmHg with 81.4% sensitivity, 88.24% specificity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.