Lepidopterism is a term that refers to a spectrum of medical conditions in humans that usually involve the skin and result from wormlike contact with an adult or larval form of specific butterflies and moths. Lepidopterism is isolated but certain people may be more prone to exposure to moths. Caterpillar's sting is not an everyday diagnosis; however, the physician should be alert and make awareness regarding caterpillar envenomation. Herein, we present the case of a 31-year-old man who presented to the hospital with a history of a caterpillar's sting associated with unilateral rashes and prickly sensation on his left thigh and lower extremity. On examination, his vitals were stable and he does not develop systemic manifestations or anaphylaxis. In view of his present compliance, he was successfully managed with antihistamines and steroids. This case is being presented not only as the event is rare but also to create awareness and it will help the clinicians to manage the case appropriately.
Cutaneous adverse reactions (CAR) can occur with any class of drugs, however more widely caused by various antibiotics. Amoxicillin is a broad-spectrum, bactericidal, beta-lactam antibiotic, widely used for combating various infections. Cutaneous drug eruptions are known to be reported common while using penicillin class of drugs, specifically among children. These immune-mediated bizarre drug eruptions were range from mild to severe drug-induced cutaneous reactions, such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). The present case reported with maculopapular, erythematous rashes induced by amoxicillin in a nine-year-old male patient. Amoxicillin was prescribed for his hyperactive respiratory disease and subsequently after three days developed generalized maculopapular erythematous rashes as a result of an antibiotic-induced skin rash. The present case is being reported to add more data, also to emphasize and gather the information for evidence-based practice and to promote efficient pharmacovigilance adverse drug reaction reporting.
Aim: To throw light on the causes and complication of hypocholesterolemia. Background: Hypocholesterolemia is defined as total cholesterol and low-density lipoprotein (LDL) level below the fifth percentile of the general population. It is usually an incidental finding on routine lipid screening and thus much clinical importance is not given to the same. Though the first case of hypocholesterolemia was published in 1911, decades have passed since then with only a handful of cases of hypocholesterolemia being reported implying either a general lack of knowledge regarding the causes and consequences of low cholesterol or a lack of awareness in the diagnosis of hypocholesterolemia. Hypocholesterolemia can be caused due to many reasons and can lead to many complications as well. Case description: We report three cases of hypocholesterolemia, which had very low levels of total cholesterol and LDL at our tertiary cardiac specialty hospital over a period of one year. Hypocholesterolemia in our cases could be attributed to a combination of statins, liver dysfunction, critical illness, and chronic inflammation. More extensive work needs to be done on this subject as the incidence of hypocholesterolemia is on the rise. Conclusion: Hypocholesterolemia is equally dangerous as compared to hypercholesterolemia and more research work needs to be undertaken in this field. Clinical significance: Understanding the causes and complications of hypocholesterolemia as well as knowing the underlying molecular basis is of crucial importance as it would provide new insights into the management of hypercholesterolemia and cardiovascular diseases in particular.
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