Introduction Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can vary among different ethnic and racial groups. Objective The objective of this paper is to study the prevalence of various manifestations of SLE in a sample of the Egyptian population. Patients and methods Information in this study was derived from the medical records of SLE patients who sought medical advice at a private clinic in Cairo from January 1980 to June 2016. Results This study included 1109 SLE patients, of whom 114 (10.3%) were males and 995 were females (89.7%). Mean age of onset was 25.89 ± 10.81 years, while the median of disease duration from the onset of the disease till the last recorded visit was 26 months. The most common cumulative manifestations were arthritis (76.7%), malar rash (48.5%), leukopenia (45.7%), and photosensitivity (45.6%). A total of 33.1% of the patients had nephritis, and neuropsychiatric lupus was present in 6.4% of the patients. Secondary antiphospholipid syndrome was present in 11.5% of the patients. Antinuclear antibody and anti-double-stranded deoxyribonucleic acid were present in 1060/1094 (96.9%) and 842/1062 (79.3%) of the patients, respectively. Antiphospholipid antibodies were present in 266/636 (41.8%) of the patients, anti-Smith in 54/240 (22.5%), anti-SSA/Ro in 61/229 (20.4%), and anti-SSB/La in 32/277 (11.6%) of the patients. Male patients had a statistically higher prevalence of nephritis ( p = 0.01), whereas arthritis and alopecia were statistically higher in females ( p = 0.012 and p = 0.006, respectively). Patients with juvenile onset had a statistically higher prevalence of nephritis and seizures ( p < 0.001 and p = 0.012, respectively). Conclusions Arthritis and malar rash represented the most common clinical manifestations. Male and juvenile-onset patients had a predilection toward a more severe disease. These results are in agreement with many studies conducted in the Middle East and worldwide. On the other hand, major organ involvement was exceptionally low, which is contradictory to several reports from the Middle East and across the globe.
With the rapid growth in mobile and wireless technologies and the availability, pervasiveness and cost effectiveness of wireless networks, mobile computers are quickly becoming the normal front-end devices for accessing enterprise data. In this paper, we are addressing the issue of efficient delivery of business decision support data in the form of summary tables to mobile clients equipped with OLAP front-end tools. Towards this, we propose a new on-demand scheduling algorithm, called SBS, that exploits both the derivation semantics among OLAP summary tables and the mobile clients' capabilities of executing simple SQL queries. It maximizes the aggregated data sharing between clients and reduces the broadcast length compared to the already existing techniques. The degree of aggregation can be tuned to control the tradeoff between access time and energy consumption. Further, the proposed scheme adapts well to different request rates, access patterns and data distributions. The algorithm effectiveness with respect to access time and power consumption is evaluated using simulation.
Backgroundand study aim: Opportunistic parasitic infections have been documented to cause serious complications among immunocompromised patients, including those undergoing hemodialysis (HD). Therefore, this study aimed to determine the prevalence of common parasitic infections and associated morbidity among the HD pediatric patients at Ain Shams University Pediatric Hemodialysis Unit. Patients and Methods:A comparative cross-sectional study was conducted on 50 HD patients and 20 apparently healthy individuals from January 2018 to March 2019. Stool samples were examined for parasites using direct smear, formol ether concentration, and staining with modified Ziehl-Neelsen stain. The serological analysis for anti-Toxoplasma IgM and IgG and complete blood count was performed. The results were correlated with the history, physical, and demographic data of the study groups. Results:The overall prevalence rate of intestinal parasitoses among patients with HD was a little bit higher than the control group (70% versus 60%, respectively) but this was statistically insignificant. Blastocystis hominis (30%), Entamoeba histolytica (28%), and Giardia lamblia (20%) were the most frequent among children with HD, with a statistically significant difference in Blastocystis hominis infection rates between patients and their counterparts. Moreover, the overall Toxoplasma gondii seroprevalence rate among patients with HD was (22%) and the anti-Toxoplasma IgM was (2%). Conclusion:The overall rate of opportunistic parasitic infections and related clinical symptoms in children with HD was slightly more frequent than in the control group. So, stool examination for intestinal parasites and Toxoplasma gondii screening should be incorporated into routine clinical care for children with HD.
Introduction: Some patients with ureteropelvic junction obstruction (UPJO) have supranormal differential renal function (snDRF). We aimed to study the outcomes of pyeloplasty in adult patients with UPJO and either snDRF or normal differential renal function (nDRF) and to identify preoperative factors responsible for the snDRF phenomenon. Materials and Methods: We retrospectively retrieved data for all patients who underwent pyeloplasty and had snDRF (differential renal function [DRF] ≥55%) and nDRF (DRF between 45 and 55%) preoperatively. Preoperative radiological data using computed tomography or magnetic resonance imaging were correlated with the presence of snDRF phenomenon. In addition, scintigraphic findings pre- and post-operatively were also assessed to evaluate the functional outcomes. Results: Of a total of 856 patients, 31 had snDRF (group 1) and 42 had nDRF (group 2). After a mean of 37 months’ follow-up in Group 1, 22 patients developed DRF reduction with non-obstructive pattern. Mean DRF % decreased from 59 ± 2.8 to 48 ± 13 ( P < 0.0001). However, in Group 2, five patients had DRF decrease. Four patients developed snDRF phenomenon postoperatively. Increased renal pelvis volume ≥50 mm 3 and increased anteroposterior pelvic diameter (APD) ≥37 mm were found to predict snDRF phenomenon. The same findings, in addition to preoperative snDRF, correlated with postoperative DRF decrease. Conclusion: SnDRF function could be expected in patients with increased renal pelvis volume and APD. The absolute value or changes in DRF are not reliable to judge treatment failure.
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