Objective: Irrational and overzealous use of antibiotics in addition to multidrug resistance has increased at an alarming limits around the world.  This study aimed to evaluate the knowledge and practices toward antibiotic use among students at Yarmouk University Material and Method: A cross-sectional descriptive survey using a structured electronic version of valid questionnaire was distributed among participants. Google form was prepared based on available questionnaire in literature, revised by a group of academic pharmacist to validate the questionnaire. Test-retest was performed for a small group and cronbach alpha was calculated. The form was distributed randomly among under- and postgraduate students at Yarmouk University via their mails. Results: A total of 1154 individuals who completed questionnaires were analyzed. The knowledge of antibiotic use and resistance was quite good; 72.7% reported correct responses with a mean score of 16 out of 22. High rates of antibiotic use were found with 92% of respondents used antibiotics in the past three months. Inappropriate practice toward antibiotic was common; 48% used it for incorrect indication (e.g., common cold, fever, and pain), 60% used for improper duration and 20% don’t take the correct doses. Conclusions: Interventions on enhancing awareness and understanding of rational antimicrobial use are highly recommended by promoting expert-driven behavioural change, effective communication, education and training. Furthermore, law restriction on antibiotic dispensing should be introduced.

Introduction Septic knee arthritis after elective arthroscopic procedures is a rare surgical emergency, with Pseudomonas aeruginosa even more rarely causing the infection. The treatment by arthroscopic debridement and lavage with diluted Povidone-Iodine has potential benefits that may be useful in improving the prognosis for patients. This case report discusses the potential benefits of using antiseptics like Povidone-Iodine in the washout of the affected joint. Presentation of case We present a patient with post arthroscopic septic knee arthritis caused by P . aeruginosa treated successfully by arthroscopic synovectomy and washout with normal saline and diluted povidone‑iodine, and prolonged antimicrobial therapy. Discussion Preceding reports of P . aeruginosa suggest intraoperative factors, postoperative factors, and host factors that may lead to this uncommon infection. There is controversy over the optimal management regarding arthroscopic versus open debridement, and the choice of the irrigating fluid. Conclusion The use of antiseptics like Povidone-Iodine in the washout procedure may lead to improved outcomes if used for a short controlled period of time and followed by copious irrigation with saline. Further studies must be done to determine the efficacy and risk-to-benefit ratio of this method.