Purpose To study treatment outcome of parathyroid adenomas using ultrasound‐guided radiofrequency ablation. Methods Twenty‐seven patients with a single adenoma of the parathyroid gland were included in the study. Using color Doppler ultrasonography, the lesion and its characteristics were determined, and dextrose was injected to dissect the gland from the surrounding structures. The ablation process was done with 6–12 watts of power. Results No complications were seen in any of the subjects. A significant reduction was seen in serum parathyroid hormone (PTH) and calcium levels after treatment. PTH levels showed a median decrease of 13.8%, and a median decrease of 8.2% was seen in serum calcium levels (p < 0.001). Phosphorus levels did not change significantly after treatment. In 1‐month follow‐up of patients, the lesion size had decreased considerably. In long‐term follow‐up, 11 of 20 patients having subsequent imaging had indistinguishable lesions. Conclusion Our results showed that RFA of parathyroid adenomas caused a significant reduction in biomedical indicators of disease and resulted in a significant reduction or disappearance of the lesion in the majority of the patients while having no considerable complications.
Background: Cumulative dose of ovary as a radiosensitive organ during abdominal and pelvic CT scan imaging is still a controversial challenge that requires practical dose reduction strategies. Although bismuth shields can reduce the dose in the right proportions, their use is controversial due to the reduced image quality. Objectives: The aim of this study was to investigate the performance of a new combination of X-ray absorber structures that have less effect on image quality parameters. Methods: First, various shields with different weight percentages of Cu and Bi were made, then the percentage of dose reduction and image quality were evaluated via phantoms. Finally, Shield with the least effect on image quality was evaluated for clinical evaluation on 20 patients. Results: Shielding with thicknesses of 1T and 3T reduced the Entrance skin dose of ovarian by about 52% and 73%, respectively. Shields with 90% cu-10% Bi and 100% Bi structures had the least and most destructive effects on image quality, respectively, and also have the same image quality. The 10% Bi-90% Cu shield provided a 21% greater dose reduction than the bismuth shield. Also, this 1T thick shield did not create an artifact in the reconstructed images. Conclusions: Shields are flexible, inexpensive, and user-friendly for ovarian shielding in abdominal and pelvic CT scans. Unlike bismuth shields, shields do not have the detrimental effects of image quality degradation.
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