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Funding Acknowledgements Type of funding sources: None. Background Home-based cardiovascular disease (CVD) primary prevention (HBPP) and cardiac rehabilitation (HBCR) programs which occupied a small proportion of the overall Preventive Cardiology work in the past have become mainstream during the COVID-19 pandemic. Purpose This study aims to analyse the effectiveness of a home-based CVD prevention program implemented during the pandemic in India. Methods A retrospective study was conducted on pre-pandemic and pandemic enrolees. Health behaviour, CVD risk factors, physical and mental component score (PCS, MCS) from SF-12 questionnaire, body mass index (BMI), 6-minute walk distance (6MWD), and clinical and biochemical parameters were assessed. A multidisciplinary team consisting of Physician, Physiotherapist, Dietician and Counselling Psychologist provided the program using tele-health platforms. Results Of the 66 subjects (55 ± 13 years, 73% male), 17 (26%) enrolled pre-pandemic and 49 (74%) enrolled during-pandemic, 28 (42%) were HBPP and 38 (58%) were HBCR participants. Majority of the subjects (n = 51, 77%), with significantly more HBCR than HBPP participants, harboured 4 or more risk factors (p = 0.04). In the 60 (91%) program completers, BMI, 6MWD, PCS and MCS had improved significantly. SBP, DBP, LVEF, HbA1c, total cholesterol and LDL had improved significantly in affected subjects. Completely home-based participants (n = 44, 67%) who never had any in-person contact with the team during the program also showed significant improvement. No adverse events were reported. Conclusion Comprehensive home-based CVD prevention programs are effective in improving anthropometric, clinical, biochemical and psychosocial parameters, are a safe alternative to conventional programs and could potentially become the standard-of-care in the post-pandemic era. Abstract Figure. Outcomes in program participants  Abstract Figure. Management of ACS in participants

Brain disorders are not confined to the western countries and their rate is increasing frequently in the Indian subcontinents, ranging from adolescents to adults. The key diseases i.e. Depression, Alzheimer's and Epilepsy are common and are predicted to upsurge in the future. Media and entertainment technologies may be the causative factors but still needs a lot of research. Conventional treatment is effective but with complementary ineligible side effects, which need an effective regimen guidelines for their use. The alternative therapeutic system is also an option to be augmented with the present therapeutic system but still needs a lot of regulation clearance. The present review deals with the current system and the best guidelines to be followed for the particular diseases.