Mid-phalangealHair, Proximal phalangeal and Seminal fluid analysis.
Background:Hair is a filamentous keratinized structure present over almost all of the body surface. It is a derivative of the epidermis which assists in thermoregulation and provides some protection against injury. Probability of incidence of hair distribution was also studied among the dorsum of phalanges of the 2 nd to 5 th fingers of both hands. Objectives: The aim of the study to assess the different patterns and frequency of the distribution of the phalangeal hair of the hands of Iraqi males' population in correlation with seminal fluid parameters. Methods: The subjects studied were (350) male. All subjects were born in Iraq and aged between 18 and 58 years. The observations were made using a hand lens in daylight. Presence or absence of hair over each phalanx of the right and left hand, age and seminal fluid analysis of each subject were recorded.
Results:The results was shown a significant difference between study group and control group in hair distribution on the dorsum of phalanges of the fingers of right and left hands. In left hand phalanges of proximal and middle (P<0.05) but on index there was non-significant (P>0.082). While significant difference (P<0.05) in proximal of right hand phalanges. Non-significant (P>0.05) in index and middle fingers of right hands Discussion: Many studies show that the majority of individuals have hair on the proximal and middle phalanges of the right and left hand but no on the distal phalanges. The highest percentage of hair distribution was observed in the proximal phalanges. The significant variation in the pattern and number of hair on the phalanges may be due to hormonal effect during intrauterine life.
Background: Successful implantation requires an intricate succession of molecular and genetic interactions. The implantation process is controlled by number of molecules like ovarian hormones, cytokines and growth factors which play an important role in regulating embryo differentiation, invasion and adhesion. During this time any breach in the communication between the endometrium and the embryo leads to implantation failure. Aim of the study: to evaluate the role of Heparin binding epidermal growth factor (HB-EGF), measured in serum and follicular fluid in prediction of pregnancy outcome of infertile women with and without PCOS. Patients and methods: A convenient sample of 100 infertile women undergoing intracytoplasmic sperm injection (ICSI) were intentionally divided, according to the cause of infertility, into 50 infertile women with polycystic ovary syndrome (PCOS) and 50 infertile women without PCOS. Heparin binding epidermal growth factor was measured on early follicular phase of the cycle (CD2-3) and at the day of ovarian pick up. Results: Highly significant(P<0.001) increase were reported between PCOS and non-PCOS groups regarding estradiol (E 2 ) and HB-EGF levels in the serum follicular phase (day 2-3) and in the FF on day of ova pickup (OPU).In PCOS women , HBEGF in the serum of follicular phase and at day of OPU with its level in the FF at day of OPU were all significantly (P<0.05) higher in women with positive pregnancy outcome than those with negative pregnancy outcome. Conclusion: Serum HB-EGF level is more valuable in predicting pregnancy out come in infertile PCOS women than non-PCOS women, and that serum HB-EGF level is more helpful than follicular fluid HB-EGF level in predicting pregnancy outcome in infertile PCOS women.
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