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The synthesis and characterization of tetraethylammonium (diorgano)halogeno(2, 6‐pyridinedicarboxylato)stannates are described. The solution structures of these complexes in CDCl3 and DMSO are discussed on the basis of 119Sn and 19F NMR data. Their in vitro antitumour activities against two human tumour cell lines, MCF‐7 and WiDr, are presented.

Diorganotin deriuatiws of dicarboxylic acids, including diethyltin propene-l,3-dicarboxylate, diethyltin homophthalate, and di-n-butyltin tetrafluorophthalate, were tested in uitro against two human tumor cell lines, MCF-7, a mammary tumor, and WiDr, a colon carcinoma. Most of these display lower inhibition doses ID,, than cis-platin. The synthesis and characterization of the last three compounds by Mossbauer spectroscopy, 'H, I3C andlor Il9Sn NMR and mass spectrometry, are also presented.

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