Electronic Health Records are rapidly gaining traction in healthcare with increased acceptance and adoption. However, there is limited understanding of factors influencing adoption in primary care. This paper investigates the human factors of EHR adoption in primary healthcare in Saudi Arabia. An online survey questionnaire was sent to all primary healthcare professionals in Riyadh city, Saudi Arabia. A 65.9% (1127/1710) response rate was obtained. The respondents demonstrated positive perceptions of EHRs in relation to the systems’ benefits. The perceptions were influenced by sociodemographic variables; hence, need consideration when implementing EHRs in primary care.