Gastro intestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastro intestinal tract [1] and account for 80 % of all GI tumors. Approximately 30% of GISTs are malignant [2]. Occurring throughout the entirety of the GI tract, GISTs most commonly present in the stomach or small intestine [3], Most GISTs present asymptomatically. They are best identified by computed tomography (CT) scan and most stain positive for CD117 (C- Kit). For localized, resectable tumors, surgical resection remains the cornerstone of treatment. For patients with locally advanced disease, preoperative imatinib can be used to help reduce tumor burden before resection [4]. We report the case of a 48 years old patient who presented a gastric stromal tumor invading the spleen, the pancreas and a portion of the left liver. After 6 months of néo adjuvant Imatinib therapy, the patient has undergone a longitudinal gastrectomy associated with splenectomy caudal pancreatectomy and left hepatectomy in which the evolution was favorable.

Annular pancreas is a rare congenital condition in which a ring of ectopic pancreatic tissue partially or completely surrounds the second part of the duodenum [1]. This Congenital anomaly is usually presented in infants and newborn, rarely in adult life. It can present in a wide range of clinical severities making it difficult to diagnose. CT scan can illustrate the pancreatic tissue encircling the duodenum. Surgery still remains necessary to confirm diagnosis and bypassing the obstructed segment. We report the case of a 22 years old female patient who presented with history of vomiting and weight loss causing a stature weight growth delay, the diagnosis was made by the CT scan. Then the patient was scheduled for a gastroenteroanastomosis. The evolution was favorable.