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Now a days. The reinforcement concretes frames are mostly used in the world. With increasing population, the land is scarce and expensive, where the high-rise building is representing the best solution for the solving the problem. The evolution of the tall buildings structural systems based on the new concepts with newly adopted high strength materials and construction methods have to developed the stiffness and lightness. recently diagrid system is adopted in the high rise building to improve efficiency and flexibility in architectural planning. In this study, the 4 models are prepared for the 12-storey building by providing open space core section in the structure is prepared with 4 different angles i.e., 50.2 0 (2-storey connection), 67.40 (4-storey connection module), 74.2 0(6- storey connection module), 820 (12 storey connection) from that finding optimum angle for the 12-storey model in all criteria. After the 12-storey building analysis, compare the results with the optimum angle for the 12-storey building and simple frame building in terms of storey displacement, storey drifts and materials consumption for different model and also apply the optimum angle for the 24-storey building of diagrid system compared with the 24-storey simple frame structure in terms of all criteria.

Background and Aims: Patient state index (PSI) and bispectral index (BIS) are depth of anesthesia monitors utilized for the dosage of propofol usage for induction. We compare PSI, BIS, and Observer’s Assessment of Alertness/Sedation Scale (OAA/S) for propofol dose usage for induction. Material and Methods: Seventy-four ASA I and II patients, aged 18–65 years scheduled for laparoscopic cholecystectomy were included and divided into groups to titrate the drug dosage of propofol needed for induction of anesthesia, monitored by PSI (Group A), BIS (Group B), or clinical OAA/S (Group C). The drug dosage needed for induction was based on a PSI value of 25 ± 2, BIS value of 48 ± 2, and OAA/S value of ≤2 as the endpoint of induction in respective groups. Intraoperative hemodynamic variables and any complications were compared. Results: The mean doses of propofol needed for induction were 2.23 mg/kg (Group A), 2.05 mg/kg (Group B), and 2.11 mg/kg (Group C). A significantly decreased dose was needed to achieve the desired end in Group B compared to Group A (P = 0.01). The hemodynamic variables such as heart rate, systolic blood pressure, and diastolic blood pressure among the three groups were comparable. Conclusion: The clinical method of titrating the dose of propofol for induction and anesthetic depth by the loss of verbal response is comparable to both BIS and PSI monitoring.