Adenomatous colonic polyps constitute a precursor for colorectal cancer. Antibodies to these precancerous lesions might identify specific early tumor antigens. Adnab-9 is a murine monoclonal antibody raised against membranes of colonic adenomas. Adnab-9 binding in colonic washings (effluent) correlates with the presence of colorectal cancer. Immunohistochemical staining with Adnab-9 shows cytoplasmic reactivity in scattered cells in 4 of 31 adenomatous tissue sections, 0 of 14 sections of colorectal cancer cells, and 1 of 8 normal-appearing colonic mucosa specimens examined. Adnab-9 recognized a dominant M(r) 87,000 protein species in tissue extracts in the membrane-bound fraction of effluent by Western blotting. Adnab-9 binding by enzyme-linked immunosorbent assay in adenomatous extracts is higher than cancer or normal tissue, is membrane-bound, and is absent from established colorectal cancer cell lines. This distribution and nature of immunostaining suggest that Adnab-9 recognizes a determinant associated with the membrane component of a subpopulation of adenoma cells which may have a role in early colorectal neoplasia.

Risk is part of every human endeavor. Risk Management area has grown many folds in past decade in direct proportion to the number of projects undertaken. The number of projects in all the sectors have increased to fulfil the quest towards a better and more and more productive, convenient and evolved life - and is termed as ‘development’ and ‘growth’. With such increase in growth rate, the number of capital and resource intensive projects have also increased across all the sectors. Today for organizations, the competition, customer expectations, and developments in automation, IT technologies and concurrent engineering methods - all are pushing the project durations to fraction of durations they used to take a decade ago. Also with improvement in skills & competencies and communication and conveyance infrastructure getting hi-tech, today more and more projects are being managed from multiple locations within country or multiple locations spread across the globe. A business with an effective risk process will experience fewer surprises as it deploys the forward-looking radar of risk management. This research work is focused on the Risk Identification step of the risk management process. Risk management is high on the agenda for forward-thinking firms due to the increased pace of change, client demands, and market globalization. In today's economy, a thorough risk management strategy is required to stay afloat.

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Multiple distant nodular cutaneous metastases from carcinoma breast is a very rare entity. In the English literature few references are present about this subject. Here we present a case of distant nodular cutaneous metastasis from carcinoma breast. KEYWORDS: Carcinoma breast, distant cutaneous metastasis. INTRODUCTION:Distant Cutaneous metastasis from carcinoma breast is a very rare entity. Often, the direct invasion of the anterior chest wall and/or local infiltration presenting as skin metastasis, although rarely seen in an area outside of the chest wall. Scalp involvement is very rare in breast cancer. (1,2) We report a case of distant nodular cutaneous metastasis to scalp over frontal region and skin over the neck from carcinoma of left breast without local breast skin or chest wall involvement and without clinically palpable axillary lymph nodes.

In general the performance of any student is measured by their achievement in their education. Only academic achievement is considered as the prime basis for admission purpose. Even in selection of different professional courses and jobs also educational achievement play a vital role. This research deals with the relationship between academic achievement and intelligence of X class students in Ramakrishnpur of Mancherial District of Telangana State of India. As per the Garrett: “Intelligence as including the abilities demanded in the solution of problems which requires the comprehension and use of symbols.” The present study is focusing on the relation between the intelligence and Academic achievement of X class students in rural area and that too from the Government school. Intelligence plays a vital role on their children’s academic achievement. Different levels of intelligence are influencing the performance and curriculum achievement of the children’s in their different levels.