Consistently nurturing job satisfaction remains a cardinal principle of most organizations. This study is designed to test the effect of both intrinsic and extrinsic motivation, organizational climate, university reputation on job satisfaction in some public universities. It is widely acknowledged that the role of motivation towards ensuring employees satisfaction is not in any doubt. Equally when complimented by a supporting environment and enhanced by requisite reputation, the issue of employee job satisfaction is amicably resolved. This paper proposes a model that links the moderating role of university reputation between motivation, organizational climate and job satisfaction. It includes supporting literatures for the proposed model in other to contextualise the study. Its contribution to knowledge rest on the fact that university reputation affects various aspects of human behaviour as well as shows the relevance and importance of reputation towards developing a healthy competitive advantage. Apart from that, university reputation is also considered and shown