Background
SARS-CoV2 virus could be potentially myopathic. Serum creatinine phosphokinase (CPK) is frequently found elevated in severe SARS-CoV2 infection, which indicates skeletal muscle damage precipitating limb weakness or even ventilatory failure.
Case presentation
We addressed such a patient in his forties presented with features of severe SARS-CoV2 pneumonia and high serum CPK. He developed severe sepsis and acute respiratory distress syndrome (ARDS) and received intravenous high dose corticosteroid and tocilizumab to counter SARS-CoV2 associated cytokine surge. After 10 days of mechanical ventilation (MV), weaning was unsuccessful albeit apparently clear lung fields, having additionally severe and symmetric limb muscle weakness. Ancillary investigations in addition with serum CPK, including electromyogram, muscle biopsy, and muscle magnetic resonance imaging (MRI) suggested acute myopathy possibly due to skeletal myositis.
Conclusion
We wish to stress that myopathogenic medication in SARS-CoV2 pneumonia should be used with caution. Additionally, serum CPK could be a potential marker to predict respiratory failure in SARS-CoV2 pneumonia as skeletal myopathy affecting chest muscles may contribute ventilatory failure on top of oxygenation failure due to SARS-CoV2 pneumonia.
Summary:Ameloblastoma is an aggressive benign odontogenic tumor of jaws with different clinical features and histologic patterns. The resection of mandible in growing young patient is associated with number of complications such as loss of jaw bone support, deformity, dysfunction and psychological distress even after reconstruction. An alternative conservative surgical procedure "Dredging Method" is a procedure which can eradicate the tumor as well as restore the normal contour and function of jaw. The procedure was followed in twenty four cases of histologically confirmed mandibular ameloblastoma in Bangladeshi patients, with recurrence of three cases in an average of two years follow up. The recurrent cases could be handled easily due to early detection in regular follow up.(J Bangladesh Coll Phys Surg 2011; 29: 72-77)
Clinical audit of indoor, Dept. of Oral and Maxillofacial Surgery, Dhaka Dental College and Hospital was performed for two years, January 2004 to December 2005. Data included all the indoor patients who were admitted for elective surgery. Day cases were excluded from the study. The audit was performed to assess the nature of pathology and number of patients admitted for surgical treatment. Bangladesh Journal of Dental Research and Education Vol.5(2) 2015: 37-39
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