Sharing metadata, individual participant data and summary data, as a complement to results dissemination and trial registration requirements, is perceived to be advantageous by enabling faster and more accurate meta-analyses and reducing the need for additional trials. To date, various models of data access have been utilized in order to manage clinical trials data sharing and access in line with the rights and interests of sponsors, researchers and patients involved in clinical trials. In order to ensure responsible data sharing, the data access review process should be developed in a way that ensures fairness, transparency and objectivity. In this article, we critically review some examples of current governance models in clinical trials data sharing and suggest approaches to ensure the objectivity of the data access review process.
The recent decline in vaccination rates across Europe has led to outbreaks of vaccine preventable diseases such as measles. Although there have always been persons opposed to vaccination, in recent years an increasing number of parents are losing confidence in or are being complacent about vaccinating their children. Given the accessibility of information on the internet, parents are actively and independently researching vaccines. They are exposed to negative claims about vaccines that appeal to their emotions and emotional stories tend make parents doubt vaccinations. By contrast, most positive vaccine messages focus on providing information through scientific data which has proven to be ineffective for some hesitant parents.Vaccine hesitancy can only be understood by looking at it from different perspectives and by exchanging knowledge between multiple fields of study. A transdisciplinary approach, in which individuals with different backgrounds search for solutions together, is necessary to be able to provide one or more solutions to the problem. Therefore, we spent eight months trying to solve part of this wicked <target target-type="page-num" id="p-93"/>problem from a transdisciplinary perspective. Based on literature reviews of different topics within vaccine hesitancy, interviews with hesitant parents, interactions with various stakeholders within and outside academia, and analyses of popular views on social media concerning vaccines, we question the effectiveness of the current pro-vaccine approaches. We also suggest adopting ‘storytelling’ that incorporates scientific data to inform parents and we argue that narratives are intrinsically persuasive as they are easier to understand and could prove more effective than traditional scientific communication. We expect that this strategy will contribute to the increase in and maintenance of high vaccination coverage rates and stop the circulation and outbreak of vaccine preventable diseases.
The World Anti-Doping Agency (WADA) sets out a detailed description of what its own conception of the "spirit of sport" as employed in the World Anti-Doping Code (WADC) entails. However, controversies as to the significance and meaning to be ascribed to the term abound in the literature. In order to unravel the core of the debates and to move discussions forward, the authors aimed at reviewing understandings of the spirit of sport in the conceptual literature. The main databases were searched using relevant keywords. After the inclusion and exclusion criteria were applied, eighteen publications were included in the review. The most striking result to emerge from the data is the multivalence of the concept of spirit of sport. Our thematic analysis generated the contestability of the spirit of sport as the predominant theme in the conceptual literature. There is a need for empirical research to generate data about perspectives on the spirit of sport from other stakeholders especially those of the athletes themselves.
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