Objectives:The aim of the current study was to evaluate the application of two advanced noise-reduction algorithms for dental micro-CT images and to implement a comparative analysis of the performance of new and current denoising algorithms. Methods: Denoising was performed using gaussian and median filters as the current filtering approaches and the block-matching and three-dimensional (BM3D) method and total variation method as the proposed new filtering techniques. The performance of the denoising methods was evaluated quantitatively using contrast-to-noise ratio (CNR), edge preserving index (EPI) and blurring indexes, as well as qualitatively using the double-stimulus continuous quality scale procedure. Results: The BM3D method had the best performance with regard to preservation of fine textural features (CNR Edge ), non-blurring of the whole image (blurring index), the clinical visual score in images with very fine features and the overall visual score for all types of images. On the other hand, the total variation method provided the best results with regard to smoothing of images in texture-free areas (CNR Tex-free ) and in preserving the edges and borders of image features (EPI). Conclusions: The BM3D method is the most reliable technique for denoising dental micro-CT images with very fine textural details, such as shallow enamel lesions, in which the preservation of the texture and fine features is of the greatest importance. On the other hand, the total variation method is the technique of choice for denoising images without very fine textural details in which the clinician or researcher is interested mainly in anatomical features and structural measurements. Dentomaxillofacial Radiology (2016Radiology ( ) 45, 20150302. doi: 10.1259 Cite this article as: Shahmoradi M, Lashgari M, Rabbani H, Qin J, Swain M. A comparative study of new and current methods for dental micro-CT image denoising. Dentomaxillofac Radiol 2016; 45: 20150302.
Estimation of missing digital information is mostly addressed by one or two-dimensional signal processing methods; however, this problem can emerge in multi-dimensional data including 3D images. Examples of 3D images dealing with missing edge information are often found using dental micro-CT, where the natural contours of dental enamel and dentine are partially dissolved or lost by caries. In this paper, we present a novel sequential approach to estimate the missing surface of an object. First, an initial correct contour is determined interactively or automatically, for the starting slice. This contour information defines the local search area and provides the overall estimation pattern for the edge candidates in the next slice. The search for edge candidates in the next slice is performed in the perpendicular direction to the obtained initial edge in order to find and label the corrupted edge candidates. Subsequently, the location information of both initial and nominated edge candidates are transformed and segregated into two independent signals (X-coordinates and Y-coordinates) and the problem is changed into error concealment. In the next step, the missing samples of these signals are estimated using a modified Tikhonov regularization model with two new terms. One term contributes in the denoising of the corrupted signal by defining an estimation model for a group of mildly destructed samples, and the other term contributes in the estimation of the missing samples with the highest similarity to the samples of the obtained signals from the previous slice. Finally, the reconstructed signals are transformed inversely to edge pixel representation. The estimated edges in each slice are considered as initial edge information for the next slice and this procedure is repeated slice by slice until the entire contour of the destructed surface is estimated. The visual results as well as quantitative results (using both contour-based and area-based metrics) for seven image datasets of tooth samples with considerable destruction of the dentin-enamel junction (DEJ) demonstrates that the proposed method can accurately interpolate the shape and the position of the missing surfaces in computed tomography images in both two and three dimensions (e.g. 14.87 ±3.87 μ m of mean distance (MD) error for the proposed method versus 7.33 ±0.27 μm of MD error between human experts and 1.25 ±~0 % error rate (ER) of the proposed method versus 0.64 ±~0 % of ER between human experts (~1% difference)).
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