Background: The aim of this study was to evaluate the longer-term results of bicuspid aortic valve (BAV) repair with or without aortic root replacement.Methods: From 1999 to 2017, 142 patients with or without aortic root dilatation who underwent repair of a regurgitant BAV were included in the study. Ninetyfour patients underwent isolated BAV repair (Group 1; median age 43 years) and 48 patients underwent valve-sparing aortic root replacement plus BAV repair (aortic valve reimplantation-Group 2; median age 48 years). Median clinical follow-up time was 5.9 years (range 0.5-15) in Group 1 and 3 years (range 0.5-16) in Group 2, respectively.Results: In-hospital mortality was 1% in Group 1, and 2% in Group 2 (p = .6). The 5-and 10-year survival was 93 ± 2.9% and 81 ± 5.8% in Group 1 and 96 ± 3.1% and 96 ± 3.1% in Group 2, respectively (p = .31). Eleven patients of Group 1 (1.7%/ patient-year) and five patients of Group 2 (2.2%/patient-year) underwent reoperation of the aortic valve (p = .5). The 5-and 10-year freedom from reoperation were 93.0 ± 2.1% and 77.1 ± 7.1% in Group 1 and 93.0 ± 5.0% and 76.7 ± 9.6% in Group 2 (p = .83), respectively. At the latest follow-up, only two patients of Group 1 and 1 patient of Group 2 had AV regurgitation = 2°(p = .7). The cumulative linearized incidence of all valve-related complications (bleeding, stroke, endocarditis, and reoperation) was 2.9%/patient-year in Group 1% and 4%/patient-year in Group 2, respectively (p = .6).Conclusions: Isolated BAV repair and combined aortic valve reimplantation plus BAV repair provide good clinical longer-term outcomes with relatively low reoperation rate and durable valve function.
Background The aim of this study was to evaluate the longer-term results
of bicuspid aortic valve (BAV) repair with or without aortic root
replacement. Methods From 1999 to 2017, 142 patients with or without
aortic root dilatation who underwent repair of a regurgitant BAV were
included in the study. Ninety-four patients underwent isolated BAV
repair (Group 1; mean age 45±14 years) and 48 patients underwent
valve-sparing aortic root replacement plus BAV repair (aortic valve
reimplantation – Group 2; mean age 49±13 years. Median follow-up time
was 5.9 years (range 0.5-15) in Group 1 and 3 years (range 0.5-16) in
Group 2, respectively. Results In-hospital mortality was 1% in group 1,
and 2% in Group 2 (p=0.6). The 5- and 10-year survival was 93±2.9% and
81±5.8% in Group 1 and 96±3.1% and 96±3.1% in Group 2, respectively
(p=0.31). Eleven patients of Group 1 (1.7% /patient-year) and 5
patients of Group 2 (2.2%/patient-year) underwent reoperation of the
aortic valve (p=0.5). The 5- and 10-year freedom from reoperation were
93.0±2.1% and 77.1±7.1% in Group 1 and 93.0±5.0% and 76.7±9.6% in
Group 2 (p=0.83), respectively. At latest follow-up only 2 patients of
Group 1 and 1 patient of Group 2 had AR=2° (p=0.7). The cumulative
linearized incidence of all valve-related complications (bleeding,
stroke, endocarditis, reoperation) was 2.9%/patient-year in Group 1 and
4%/patient-year in Group 2, respectively (p=0.6). Conclusions Isolated
BAV repair and combined aortic valve reimplantation plus BAV repair
provide good clinical longer-term outcomes with relatively low
reoperation rate and durable valve function.
We read the letter to the editor by Dr Jasinski et al. entitled "Long-term durability of valve-sparing or repair procedures in BAV-Is there room for improvement?" with great interest.
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