This experiment was conducted to investigate the effects of different levels of colostrum powder on performance, intestinal morphology, blood biochemical parameters and antioxidant status of broilers in heat stress. In this experiment 224 Ross-308 broiler chicks were used from 1 to 42 days in 5 treatments and 4 replicates (12 birds per replicate) in a completely randomized design. Treatments included: 1) control (without using colostrum), 2) 0.5% of colostrum, 3) 1% of colostrum, 4) 1.5% of colostrum, and 5) 2% of colostrum powder. Colostrum powder was added in first 10 days of broilers breeding period in their diets. Colostrum powder had significant effects on performance, carcass traits and intestinal cells morphology of broilers in heat stress (P < 0.05). In grower period the highest amounts of final body weight and body weight gain were obtained with 2% of colostrum powder. Colostrum powder in contrast to control improved the percentages of gizzard, liver, bursa of fabricious, thighs and breast (P > 0.05). The highest villies, the lowest crypts and the highest ratio of villies/crypts were obtained with colostrum powder adding (P > 0.05). Colostrum powder had no significant effects on blood biochemical parameters and antioxidant status of broilers. The overall resulted showed that in broilers in heat stress condition using colostrum powder up to 2% in starter period has beneficial effects on performance, carcass traits and intestinal morphology of broilers.