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In this paper, the problem of constructing an efficient quantum circuit for the implementation of an arbitrary quantum computation is addressed. To this end, a basic block based on the cosine-sine decomposition method is suggested which contains $l$ qubits. In addition, a previously proposed quantum-logic synthesis method based on quantum Shannon decomposition is recursively applied to reach unitary gates over $l$ qubits. Then, the basic block is used and some optimizations are applied to remove redundant gates. It is shown that the exact value of $l$ affects the number of one-qubit and CNOT gates in the proposed method. In comparison to the previous synthesis methods, the value of $l$ is examined consequently to improve either the number of CNOT gates or the total number of gates. The proposed approach is further analyzed by considering the nearest neighbor limitation. According to our evaluation, the number of CNOT gates is increased by at most a factor of $\frac{5}{3}$ if the nearest neighbor interaction is applied.

An elementary flux mode (EFM) is a pathway with minimum set of reactions that are functional in steady-state constrained space. Due to the high computational complexity of calculating EFMs, different approaches have been proposed to find these flux-balanced pathways. In this paper, an approach to find a subset of EFMs is proposed based on a graph data model. The given metabolic network is mapped to the graph model and decisions for reaction inclusion can be made based on metabolites and their associated reactions. This notion makes the approach more convenient to categorize the output pathways. Implications of the proposed method on metabolic networks are discussed.

Abstract-Quantum logic decomposition refers to decomposing a given quantum gate to a set of physically implementable gates. An approach has been presented to decompose arbitrary diagonal quantum gates to a set of multiplexed-rotation gates around z axis. In this paper, a special class of diagonal quantum gates, namely diagonal Hermitian quantum gates, is considered and a new perspective to the decomposition problem with respect to decomposing these gates is presented. It is first shown that these gates can be decomposed to a set that solely consists of multiple-controlled Z gates. Then a binary representation for the diagonal Hermitian gates is introduced. It is shown that the binary representations of multiple-controlled Z gates form a basis for the vector space that is produced by the binary representations of all diagonal Hermitian quantum gates. Moreover, the problem of decomposing a given diagonal Hermitian gate is mapped to the problem of writing its binary representation in the specific basis mentioned above. Moreover, CZ gate is suggested to be the two-qubit gate in the decomposition library, instead of previously used CNOT gate. Experimental results show that the proposed approach can lead to circuits with lower costs in comparison with the previous ones.

In this paper, simultaneous reduction of circuit depth and synthesis cost of reversible circuits in quantum technologies with limited interaction is addressed. We developed a cycle-based synthesis algorithm which uses negative controls and limited distance between gate lines. To improve circuit depth, a new parallel structure is introduced in which before synthesis a set of disjoint cycles are extracted from the input specification and distributed into some subsets. The cycles of each subset are synthesized independently on different sets of ancillae. Accordingly, each disjoint set can be synthesized by different synthesis methods. Our analysis shows that the best worst-case synthesis cost of reversible circuits in the linear nearest neighbor architecture is improved by the proposed approach. Our experimental results reveal the effectiveness of the proposed approach to reduce cost and circuit depth for several benchmarks.