Background: Pre-eclampsia is a multisystemic pregnancy condition marked by additional organ systems being involved, elevated blood pressure, and negative consequences on the fetus's health. Using nonpharmacological strategies, such as the finger portable relaxation technique, may be a way to reduce fatigue and stress. This study aimed to evaluate the effect of the finger handheld relaxation technique on fatigue and stress among women with preeclampsia. Subjects and Method: Study design: -Quasiexperimental design study &control group was used in the present study. Setting: The research will be carried out in the obstetric department at Mansoura University Hospital, Egypt. Subjects: The study subjects included a purposive sampling technique enrolled to select a sample of 100 pre-eclamptic women in the previously selected department and who agreed to participate in the study and randomly assigned into two equal groups, with 50 pre-eclamptic women in each group (the experimental and control groups). Tools of data collection: Three tools were used for data collection; Tool I: structured Interview questionnaire to identify data related to women's personal and reproductive history, Tool II: A fatigue assessment scale, and Tool III: Cohen's Perceived Stress Scale Short Version (PSS-10). Results: Indicated that; post the application of the finger handheld relaxation technique significantly reduced fatigue and stress among women with preeclampsia in the experimental group compared to the control group. Conclusion: The study concluded that; the finger handheld relaxation technique has a significant effect on reducing fatigue and stress among women with preeclampsia. Recommendations: The finger handheld relaxation technique should be integrated into the care of women with preeclampsia to help reduce fatigue and stress.