HighlightsSSR is mainly caused by one of three conditions: hematological malignancies, infectious diseases, and other inflammatory or neoplastic disorders.CML is one of the main causes of SSR along with Hodgkin lymphoma.Three mechanisms are believed to cause SSR: parenchymal congestion and concomitant coagulopathy, leadingto splenic hemorrhage and infarction.In only 19 % of reported cases, SSR was diagnosed correctly; most common differential diagnoses include hepatic and biliary pathologies.Timely diagnosis and treatment improves survival rate and reduces complications.
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