Clinical studies reporting erectile function outcomes after localized prostate cancer treatment often demonstrate poorly interpretable and inconsistent manners of assessment as well as widely disparate rates of erectile dysfunction and erectile function. Future studies must apply scientifically rigorous methodology and standard outcomes measures to advance this field of study.

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The positron-emitting glucose analogue l8F-2-fluoro-2-deoxy-d-g1ucose (FDG) was evaluated for its accretion into the following subcutaneous human tumor xenografts in nude mice: B-cell lymphoma (Namalwa or Raji), ovarian carcinoma (HTB77), colon cancer (SW948), choriocarcinoma (BEWO), bladder cancer (UM-UC-2), renal cell carcinoma (UM-RC-3), neuroblastoma (Mey), melanoma (HTB63), and small cell lung carcinoma (NCI69). Two hours postinjection, tumor uptakes ranged from 0.027 (colon cancer) to 0.125% kg injected dose/g (melanoma); and was greater than 0.085 in the Namalwa lymphomas and the renal cell carcinomas. Tumor-blood ratios of up to 23:l were seen 2 hours postinjection (melanoma) with a mean tumor-blood ratio for all tumors of 12.3 + 1.8. Uptake in the other tumors was intermediate. When evaluated, tumor uptake was slightly greater at 1 than at 2 hours postinjection, although target-background ratios were generally higher at 2 hours postinjection. This compound, FDG, may have broad applicability as a tracer for positron-emission tomographic imaging of many human malignancies. Cancer 67:1544-1550,1991, NONINVASIVE METHOD to detect and localize tU-A mors accurately for staging purposes and to replicably quantitate their metabolic activity would be of great clinical value. Positron-emission tomography (PET), a nuclear-medicine technique detecting the dual-emission of annihilation photons (from the interaction of positrons with electrons) after nuclear decay of a positron-emitting labeled tracer, has the potential to be such a technique, due to its quantitative tomographic imaging capabilities and excellent resolution.' Although PET scanning has From the

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