Background: While the Yale-Brown Obsessive-Compulsive Scale Second Edition (Y-BOCS-II) is the gold-standard for measurement of obsessive-compulsive (OC) symptom severity, its factor structure is still a matter of debate and, most importantly, criterion validity for diagnosis of OC disorder (OCD) has not been tested. This study aimed to clarify factor structure and criterion validity of the Y-BOCS-II.Methods: We first validated and quantified the psychometric properties of a culturally adapted Portuguese translation of the Y-BOCS-II (PY-BOCS-II). The PY-BOCS-II and other psychometric instruments, including the OCD subscale of the Structured Clinical Interview for the DSM-IV, used to define OCD diagnosis, were administered to 187 participants (52 patients with OCD, 18 with other mood and anxiety disorders and 117 healthy subjects). In a subsample of 20 OCD patients and the 18 patients with other diagnoses, PY-BOCS-II was applied by clinicians blinded to diagnosis.Results: PY-BOCS-II had excellent internal consistency (Cronbach's α = 0.96) and very good test-retest reliability (Pearson's r = 0.94). Exploratory factor analysis revealed a two-factor structure with loadings consistent with the Obsessions and Compulsions subscales, and there was good to acceptable convergent and divergent validity. Importantly, the area under the curve (AUC) of the receiver operating characteristic (ROC) curve suggested elevated accuracy in discriminating between patients with OCD and control subjects (AUC = 0.96; 95% confidence interval [CI]: 0.92–0.99), that was retained in comparisons with age, gender and education matched controls (AUC = 0.95; 95% CI: 0.91–0.99), as well as with patients with other mood and anxiety disorders (AUC = 0.93; 95% CI: 0.84–1). Additionally, a cut-off score of 13 had optimal discriminatory ability for the diagnosis of OCD, with sensitivity ranging between 85 and 90%, and specificity between 94 and 97%, respectively when all samples or only the clinical samples were considered.Conclusion: The PY-BOCS-II has excellent psychometric properties to assess the severity of obsessive-compulsive symptoms, reflecting obsessive, and compulsive dimensions, compatible with currently defined subscales. Furthermore, we found that a cut-off of 13 for the Y-BOCS-II total score has good to excellent sensitivity and specificity for the diagnosis of OCD.
Objetivou-se a elaboração e a avaliação sensorial, química, física e físico-química de iogurtes de leite de cabra adicionados de polpa de umbu. Foram utilizados, na elaboração das amostras, iogurte de leite de cabra, polpa de umbu, adicionada nas proporções de 10, 15 e 20%, e sacarose. Realizou-se a caracterização química, física e físico-química da polpa do umbu utilizada na elaboração das amostras e os resultados foram expressos em média simples. Nos iogurtes adicionados de polpa de umbu realizou-se a análise sensorial por meio de escala hedônica de nove pontos, na qual foram avaliados os atributos consistência, sabor, cor, aroma, aparência, acidez e doçura e aplicados testes de aceitação; os dados foram tratados com os programas Consensor 1.1 e Assistat, com comparação entre as médias, pelo teste de Tukey. A polpa de umbu apresentou valores de pH, acidez total titulável, sólidos solúveis totais, ácido ascórbico e teor de água próximos aos valores reportados em literatura; a cor apresentou predominância do matiz amarelo. Para os iogurtes com polpa de umbu o que apresentou as maiores notas médias em todos os parâmetros da avaliação sensorial, foi o elaborado com 10% de polpa de umbu. Com base nos valores do pH, os iogurtes foram classificados como ácidos; em relação aos parâmetros acidez total titulável e ácido ascórbico, o iogurte de leite de cabra, com 10% de polpa de umbu apresentou os maiores valores; não houve diferença significativa entre as formulações em relação aos sólidos solúveis totais (°Brix), proteínas, lipídios e atividade de água.
Introduction: The prevalence of alcohol abuse increased over 10% in the last decade, with special impact in women. It is not known how the characteristics of suicide attempts vary with different forms of alcohol involvement. The aim of this study is to clarify the role of alcohol use disorder and acute alcohol consumption in suicide attempts. Objectives: Perform a brief literature review on the alcohol use disorders and suicide behaviours in those patients. Methods: A PubMed database review, with 'alcoholism" and 'suicide attempts" as keywords. Results: Alcohol abuse and suicide may be intimately linked. This association is related to impulsivity, aggression, social norm transgression, poor judgment, abnormal speech, perceptual blunting and increased pain threshold, which may all contribute to the suicide attempt. Moreover, mental disorders (particularly depression) are often associated with suicide. The lifetime prevalence of suicide attempts in patients with alcohol dependence is about 40% and mortality for suicide is 7%. Thus, patients with alcohol abuse should be screened for psychiatric symptoms and suicidality. Clinicians should assess the severity of suicidal symptoms and other depressive signs and symptoms in patients with alcohol abuse. Conclusions: Suicide attempts are common in patients with alcohol use disorder. Future studies should contribute to a deeper knowledge of these events and respective treatment.
Aim: To describe patterns of and associations between psychoactive substance use and perception of mental health status amongst male prisoners. Method: Participants consisted of 60 male prisoners, with a mean age of 38.5 (SD = 11.0). A standardised interview with three sections was carried out: 1) socio-demographic variables, 2) perception of mental health status by CORE-OM, 3) evaluation of psychoactive substance use and dependence (tobacco, alcohol, and illegal drugs).
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