The study provides empirical evidence on the mediating effects of job satisfaction (JS) and the moderating role of Islamic work ethics(IWE) when counterproductive work behaviour (CWB) is predicted by psychological contract breach (PCB) in the context of the publicministries of the Gaza Strip, Palestine. The researchers used selfadministered questionnaires to collect data from 256 managers. Thedata gathered was analysed using Partial Least Square Structural Equation Modelling (PLS-SEM). The results confirmed IWE as amoderator between PCB and JS as well as JS being a positive mediator in the PCB–CWB relationship. However, the direct relationship between PCB and CWB was insignificant. Based on these results, we point out the theoretical and practical implications of the study as well as its limitations and our recommendations for further studies.