Objective. To provide a systematic review of the social consequences of COVID-19 pandemic. Methods. In the present study, articles indexed in Persian and Latin databases (Web Of Science, Scopus, PubMed, Embase, Google Scholar and Magiran). 43 documents published in the last 3 years in Persian or English language were reviewed. The research steps were performed according to PRISMA writing standard and the quality assessment was done by two researchers independently with Newcastle Ottawa Scale tools for observational studies according to the inclusion criteria. Results. Measures to break the chain of virus transmission and to control the COVID-19 pandemic have caused major problems in the economic, social, political and psychological spheres and have affected billions of people worldwide. The COVID-19 pandemic crisis has caused widespread unrest in society and unprecedented changes in lifestyle, work and social interactions, and increasing social distance has severely affected human relations. Conclusion. The COVID-19 pandemic has social consequences in certain groups can exacerbate their unfavorable situation. Special groups in crisis situations should be given more attention, and clear and precise policies and programs should be developed to support them