Background: People who have underlying medical conditions and those over 60 years old have a higher risk of developing coronavirus disease complications (COVID-19) with more mortality rate. Breathing exercises is good for clearing the mucus from lungs and improves chest expansion while circulatory exercises enhance cardiopulmonary/vascular systems. Aim: This study aims to suggest exercise program for prevention, decrease morbidity and mortality in COVID-19 patients and patients with other respiratory co-morbidities. Conclusion: Regular simple exercises include respiratory and circulatory exercises may have a great effect on improving lung function and immunity in addition to relieving psychological stress thus can help in treatment of high risk people from COVID-19.