BackgroundInfertility is a common health problem worldwide and many researchers have worked hard to figure out its statistics and causes. Aim The aim of this study was to determine the different patterns of spermiograms among infertile men in the Suez Canal and Sinai regions. Patients and methodsThis was a descriptive cross-sectional study in which 535 infertile Egyptian patients living in the Suez Canal and Sinai regions were examined after obtaining informed consent. History taking, clinical examination, semen analysis, and other related investigations were carried out. The semen parameters were measured both dynamically and morphologically using computer-assisted semen analysis technology, according to WHO criteria (2010). ResultsThe total number of patients was 535, of whom 123 (22.9%) were normozoospermic, 40 (7.5%) were oligozoospermic, 125 (23.4%) were asthenozoospermic, 161 (30.1%) were oligoasthenozoospermic, 76 (14.2%) were azoospermic, eight (1.5%) were oligoasthenoteratozoospermic, and two (0.4%) were teratozoospermic. ConclusionThe semen parameters in the study population were markedly different from those reported in other international studies, which could be attributed to differences in many factors, such as demographic characteristics, region, lifestyle, environment, and using the new WHO (2010) criteria of semen analysis.