Introduction: Depression is the most common psychological problems in hemodialysis patients that may lead to decreased quality of life and increased mortality rate. The aim of this study was to investigate the effect of foot reflexology on depression in patients undergoing hemodialysis. Methods: This clinical trial conducted on 78 patients who were admitted to hemodialysis wards in Imam Ali hospital and Iran Mehr Clinic of Bojnord City. Probability convenient sampling technique was used to select the sample. The patients randomly assigned to three groups including: experimental, control and placebo groups. Beck Depression questionnaire was used to measure the level of depression before and after the intervention. Foot reflexology was done in the experimental group, a simple foot massage without pushing standard reflexology points in placebo group, and the routine care in control group was conducted. Data analysis was done using SPSS 16 and ANOVA. Results: Mean depression score for patients in the experimental group, placebo group and control group were: (P < 0.001), (P = 0.016), and (P = 0.042), respectively. The depression was increased in the intervention and placebo group and had a reduction in the control group. Conclusions: Reflexology is an effective medical intervention in reducing depression in patients undergoing hemodialysis.

Dehydration and malignancies are known as the most frequent predisposing factors of cerebral venous sinus thrombosis in older adults despite the fact that 30% of them remain idiopathic cerebral venous thrombosis (CVT) cases with no clear etiology. Cases of left sigmoid sinus involvement were rarely reported. Herein, an elderly case of sigmoid sinus thrombosis with unilateral hearing loss with chronic varicose vein in the leg was reported. Sigmoid sinus thrombosis that affects hearing is one of the rare complications of otitis media. Whether or not a large chronic varicose vein in the leg can serve as a predisposing factor for CVT requires further studies. Successful management of anticoagulant therapy prevented serious complications in the patient.

Introduction: We report a rare case of non-insulin secreting malignant insulinoma of the pancreas and discuss its medical and surgical management. Case Presentation: Our patient was a 62- year-old Persian female. Over the previous year, she had developed increased abdominal mass, dizziness, weakness, and fatigue. After surgical operation, chemotherapy was given to the patient. Treatment with cisplatin and etoposide was commenced in a 4-month course. Conclusion: As a result, chemotherapy showed an important role in the management of insulinoma.

Introduction: Fatigue is one of the most annoying complaints reported in people undergoing hemodialysis. However, the lack of awareness of health care providers about evidence-based interventions in one hand   and unavailability of information in a coherent manner on the other hand is an important barrier to taking more effective measures. Therefore, it was decided to investigate evidence-based nursing interventions on the fatigue of hemodialysis patients in Iran. Methods: Data collection in this systematic review study was conducted without any time limit in both Persian and English articles by searching on different databases of Iran medical articles bank such as IranDoc databases, elmnet, SID, Google scholar, Magiran, PubMed, Library Cochrane CINAHL, and Scopus. Finally, the findings of each study were entered into the data entry form as a data collection tool. Results: Out of 119 available articles, 25 related articles were reviewed. These studies were conducted between 2012 to 2019.Various interventions such as massage therapy, aromatherapy, care patterns, nutrition therapy, exercise and laugh therapy have been investigated to reduce the fatigue of hemodialysis patients. The results of studies on fatigue reduction have shown that all the proposed interventions can be effective in reducing the fatigue of hemodialysis patients. Conclusion: A look at the evidence-based interventions of various studies shows an increased tendency to control health using complementary medicine and it expresses the importance of combining complementary and clinical medicine, however, its use in hospitals has been neglected.

The article's abstract is not available.