The natural local
porosity variation in the native tissue can be
replicated by graded porosity scaffolds. Scaffolds with radial porosity
distribution can be a solution to improve both mechanical and biological
functions of the biomimetic scaffolds. In the present study, fluid
permeability as a quantitative indicator of biological performance
is studied numerically and experimentally for different pore shapes
and porosity distribution patterns in the scaffolds designed on the
basis of triply periodic minimal surfaces (TPMSs). Among the uniform
porosity scaffolds, those designed on the basis of P* (P surface)
and Y** (G surface) showed the highest permeability. In the radially
graded porosity scaffolds with linear porosity distribution, permeability
was found to be about twice more sensitive to the peripheral porosity
than the porosity at the center. The results suggest that the permeability-gradient
parameter relationships can follow different trends depending on the
pore shape as opposed to the conventional uniform porosity scaffolds.
This implies the need for the design maps that were developed to choose
appropriate scaffold pore design parameters. Finally, experimental
permeability measurement was performed via a constant head permeability
test, and the effect of test parameters (i.e., fluid height) was discussed.
Unsteady settling behavior of solid spherical particles falling in water as a Newtonian fluid is investigated in this research. Least square method (LSM), Galerkin method, LSM-Padé, and numerical model are applied to analyze the characteristics of the particles motion. The influence of physical parameters on terminal velocity is discussed and it is showed that LSM and Galerkin method are efficient techniques for solving the governing equation. Among these methods, LSM-Padé demonstrates the best agreement with numerical results. The novelty of this work is to introduce new analytical methods for solving the non-linear equation of sedimentation applicable in many industrial and chemical applications.
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