Background: Congenital malformation is responsible for spontaneous abortion, the birth of a child born dead or a child with disabilities that can lead to long-term disability and have a detrimental impact on the individual, his family and society. The etiologies are diverse. The discovery in our maternity is not rare. The absence and high cost of these prenatal diagnostic are a brake on the detection of congenital malformations. It is these various malformations diagnosed in the ante natal and at birth in our service that we describe in this work which aims to make their panorama.Methods: The purpose of this cross-sectional and descriptive study curried out between 1 January 2003 and 31 December 2013 (10 years) was to describe the various congenital malformations observed at the maternity of the Gynecology and Obstetrics ward of the Treichville University Hospital Center and to identify the socio-demographic characteristics of mothers. This study concerned all women who had given birth at the Treichville University Hospital Center and whose child had a malformation.Results: During the period, 151 parturients gave birth to at least one child with a congenital malformation and among 30,698 newborns, 161 newborns (0.52%) had a malformation. Pregnant women were between 20 and 30 years old (66%), were primiparous in 46.4% of the cases, and 41.7% were housewives. The malformations were isolated in 101 newborns (62.4%), multiple in 60 newborns (37.6%), and dominated by those of the osteoarticular system and the nervous system. Fetal malformations had a poor prognosis in 77 cases (48%) and the fetus was stillborn in 44 cases (27%).Conclusions: Congenital malformations are a reality at the maternity clinic at Treichville. In our countries, the ultrasound stays a fundamental element for the congenital diagnosis of the malformations. A good training of the doctors in prenatal diagnosis is also necessary to make of good diagnoses who will allow a better care of new-born.

Objectives: This study aimed to describe the epidemiological characteristics of metastatic relapse in breast cancer at the University and Hospital Center of Treichville. Methodology: This is a cohort and retrospective study conducted from January 2000 to December 2015 on 178 patients with metastaticrelapse in breast cancer. Results: The prevalence of metastatic relapses was 49% and the patients had an average age of 53.4 years and among them, 91.6% received school education and 88.2% did not have a high socioeconomic level. The majority of initial tumors were in Stage III (47.8%), SBR III (47.2%), High Ki 67 (46.5%), Negative RH (79.3%), and HER2 negative (58%). Metastases were generally unique (62.9%), dominated by bone sites (36.6%), with an average occurrencedelay of 2.4 years. After the occurrence of metastases, the cumulative survival rate was 5% at 3 years, and nil at 5 years. Conclusion: Metastatic relapses were common with poor prognosis.

Background: The elimination of HIV transmission from mother to child is currently possible. Côte d'Ivoire, which has a 4.6% HIV prevalence among women, is one of 22 pilot countries for the elimination of mother-to-child transmission of HIV. Since 2015, Côte d'Ivoire has adopted new strategies according to the WHO B+ guidelines. Objective: To identify factors associated with mother-to-child HIV transmission in children born of seropositive mothers managed at Treichville university hospital. Material and methods: A case-control study was conducted in the obstetrics department at Treichville university hospital, between January 2013 and December 2015. It involved children born to mothers infected with HIV, whose first PCR (Polymerase Chain Reaction) result was available during this period. A standardized questionnaire on data related to exposed children and their mother was used. Factors associated with mother-to-child HIV transmission were investigated using logistic regression. Results: A total of 214 HIV-exposed children were included in the study with a sex ratio of 0.9. The majority of the children were born by vaginal route (52.8%) and received post-exposure prophylaxis (88.3%) and replacement feed (51.9%). Their mothers received antiretroviral therapy during pregnancy in 45.3% of the cases. The first PCR was performed at the sixth week of life in 52.3% of cases. The prevalence of HIV infection in exposed children was 7.5% (95% CI = 4.5% -11.8%). In multivariate analysis, the absence of antiretroviral prophylaxis in children [aOR = 4.3, 95% (1.2 to 15.6), p = 0.03], the mixed feed [aOR = 3.8, 95% (1.1 -13.1), p < 0.03], the failure to take antiretroviral regimen during pregnancy [aOR = 8.0, 95% CI (1.9 -32.4), p < 0.003], were associated with mother-child HIV transmission. Conclusion: The mother-to-child HIV transmission rate remains high in our practice. Strategies to reduce situations that do not comply with current How to cite this paper:

Background: The management of infertile couples has seen many advances characterized today by the different techniques of medically assisted procreation (MAP) that are increasingly practiced in the developed countries. The objective of present study is to describe our experience of multicentric management of infertile couples in our ivorian context.Methods: This is a retrospective and cohort study with descriptive purpose over 210 couples treated for infertility in the gynecology services of the University and Hospital Center of Treichville and a private clinic in Abidjan, from 1st February 2013 to 31st January 2017 (48 months).Results: The frequency of infertility was 14%, and the average age was 34.3 years for women and 43.2 years for men. The etiologies were found in 199 couples (94.8%), particularly in 136 women and 113 men. The main causes were uterine (58.1%), and hormonal (26.5%) in women and of infectious origin in men (79.7%). The majority of the patients (113 women and 97 men) received an etiologic treatment, dominated by myomectomia in women (67 patients) and targeted antiobitherapy in men (84.5%). Moreover 113 couples (53.8%) received a medically assisted procreation. After the management 110 couples (52.4%) got pregnant.Conclusions: The multicenter management has enabled infertile couples to have access to modern methods in their care.

Objective: Describe the occurrence delays of metastatic relapses of breast cancer based on the characteristics of the original tumor. Methodology: This is a retrospective and cohort study conducted from January 2000 to December 2015 on patients with metastatic relapse of breast cancer. Results: Out of 178 patients collected, the metastatic relapses were estimated at 49%, occurring in patients with an average age of 53.4 years. The majority of the patients was educated (91.6%) and did not have a high socioeconomic level (88.2%). The initial tumors were mainly at a clinical stage III (47.8%), SBR grade III (47.2%), high index Ki 67 (46.5%), negative RH (79.3%) and HER2 negative (58%). Metastases were unique in general (62.9%), dominated by bone locations (36.6%), with an average age of occurrence of 2.4 years. After the occurrence of these metastases, the cumulative survival rate was 5% at 3 years, and zero to 5 years. Conclusion: Metastatic relapses were common with poor prognosis.