Hyperglycemia is an important risk factor for ROP that can be prevented along with other risk factors by accurate supervision.

Background:Umbilical arterial blood gas (UABG) analysis is more objective than other methods for predicting neonatal outcome. Acidemic neonates may be at risk for unfavorable outcome after birth, but all neonates with abnormal arterial blood gas (ABG) analysis do not always have poor outcome.Objectives:This study was carried out to determine the short term outcome of the neonates born with an abnormal ABG.Patients and Methods:In a cohort prospective study 120 high risk mother-neonate pairs were enrolled and UABG was taken immediately after birth. All neonates with an umbilical cord pH less than 7.2 were considered as case group and more than 7.2 as controls. Outcomes like need to resuscitation, admission to newborn services and/or NICU), seizure occurrence, hypoxic ischemic encephalopathy (HIE), delayed initiation of oral feeding and length of hospital stay were recorded and compared between the two groups. P value less than 0.05 was considered as being significant.Results:Comparison of short term outcomes between normal and abnormal ABG groups were as the fallowing: need for advanced resuscitation 4 vs. 0 (P = 0.001), NICU admission 16 vs. 4 (P = 0.001), convulsion 2 vs. 0 (P = 0.496), HIE 17 vs. 4 (P = 0.002), delay to start oral feeding 16 vs. 4 (P = 0.001), mean hospital stay 4 vs. 3 days (P = 0.001). None of the neonates died in study groups.Conclusions:An umbilical cord PH less than 7.2 immediately after birth can be used as a prognostic factor for unfavorable short term outcome in newborns.

The aims of this study were to determine the prevalence of dental caries in three to four-year-old children born pre-term and with a low birth weight (PLBW) to be compared with normal birth-weight children (NBW) and further to investigate the impact of relative risk factors on the development of dental caries in primary teeth. Methods and Materials: This cross-sectional case-control study was conducted on 90 children (45 PLBW and 45 NBW). The demographic data and information about feeding practices was ascertained using a structured questionnaire. Dental caries status (dmft) was determined, and the differences between the two groups were tested using the Fisher's exact and the Mann-Whitney U tests at a confidence level of 5%. Results: Twenty-five children (eight PLBW and 17 NBW) were caries free, and the mean±SD dmft was 2.5±0.3 in PLBW and 2.2±0.4 in NBW children (p>0.05). The length of feeding in PLBW children was lower than the NBW group (p>0.05). Conclusion: The prevalence of dental caries did not differ between the PLBW and NBW children. Clinical Significance: Enamel hypoplasia and snacking were not common in PLBW children which may account for the lack of difference in dental caries between the two groups.

Objective:Phototherapy is the most common treatment used for severe jaundice. There is increasing evidence that phototherapy can directly affect the expression and function of cell surface receptors including adhesion molecules, cytokines, and growth factor receptors. The aim of this study is to investigate the effect of phototherapy use on the levels of interleukin (IL)-1α, IL-6, and tumor necrosis factor (TNF)-α as cytokine expressions from keratinocytes, and also white blood cell counts in the treatment of neonate with hyperbilirubinemia.Materials and Methods:We studied 32 term newborns with hyperbilirubinemia. Blood samples were obtained before and 72 h after phototherapy. Serum levels of IL-1α, IL-6, TNF-α, and WBC count were measured in the samples using appropriate methods.Results:Serum TNF-α at 72 h of exposure to phototherapy increased, while the levels of IL-1α and IL-6 at the same time were decreased. These changes were not statistically significant. WBC counts rose significantly with phototherapy.Conclusion:Phototherapy in term neonate does not affect cytokines’ levels, but can raise peripheral WBC count.

Background:Mother's milk plays an important role in infant's health, and World Health Organization (WHO) recommends infants should be breastfed for 2 years or up.Aim:The main objective of this study was to evaluate the breastfeeding status based on parents’ educational level with comparison between Turkman and non-Turkman ethnic groups in the North of Iran in 2010.Subjects and Methods:This is a descriptive, cross-sectional study, which was carried out on 6519 subjects (3897 = non-Turkman and 2622 = Turkman) in urban and rural areas. Data have been collected through interviewing with primary school children's mothers. The schools and students were selected using multi-cluster random sampling methods. Breastfeeding was defined based on WHO predominant definition.Results:Of all mothers, 5.8% (377/6519) breastfed for 6 months, 34.8% (2265/6519) for 7-18 months, 57.4% (3745/6519) for 18-24 months and 2% (132/6519) didn’t breastfeed their infants. Breastfeeding prevalence at 19-24 months in Turkman ethnic group (64.7%; 1696/2622) was significantly more than in non-Turkman ethnic group (52.6%; 2049/3897) (P < 0.01) besides early weaning prevalence (at 6 months) in Turkman group was significantly less than in non-Turkman group (4.7%; 123/2622 vs. 6.5%; 254/3897) (P < 0.01). Odds ratio for weaning before 6 months in non-Turkman mothers were 0.563 (0.365-0.786, confidence interval [CI] 95%) in 1-12 years schooling and 0.665 (0.486-0.910, CI: 95%) in uneducated groups compared to college educated. This ratio in Turkman fathers was 3.413 (1.726-6.746, CI: 95%) in 1-12 years schooling compared with college educated.Conclusion:The duration of breastfeeding was longer among Turkman compared with non-Turkman mothers, and longer duration of breastfeeding was associated with higher educational level in the Turkman but not in the non-Turkman mothers.