The COVID-19 vaccine has been made available for emergency use in Bangladesh. However, willingness to receive the vaccine may be affected by varying factors across the country. Therefore, this study aimed to investigate the factors that influence willingness to receive the vaccine among Bangladeshi adults. A population-based cross-sectional online survey was conducted among a sample of 1,725 Bangladesh adults (age 18 years and older). The statistical analysis included univariate, bivariate and multivariate regression model. Findings show that 85% ( n = 1463) of respondents were willing to receive the vaccine. Respondents with 1–2 children (aOR: 1.77, 95% CI: 1.00–3.13, P = . 048), perceived risk of being infected (aOR: 1.48, 95% CI: 1.03–2.14, P = . 03), perceived impact on daily life (aOR: 2.53, 95%CI: 1.45–4.44, P = . 001), history of co-morbidities (aOR: 2.04, 95% CI: 1.37–3.04, P < . 01), price of the vaccine (aOR: 3.58, 95% CI: 2.34–5.47), physician’s recommendation to receive vaccine (aOR: 2.06, 95% CI: 1.38–3.06, P < . 01), vaccines supplied by government (aOR: 2.31, 95% CI: 1.64–3.25, P < . 01) were found to be motivating factors for willingness to receive the vaccine. Findings indicate that willingness to receive the vaccine is likely to be affected by socio-demographic, and health system factors. This should be carefully considered in the rollout of the vaccination plans in Bangladesh.

COVID-19 pandemic has caused global healthcare and economic crises and mass vaccination to acquire herd immunity seem to be the only solution. Present study aimed to evaluate the intent of Pakistani population towards vaccination and to uncover the barriers associated with vaccine reluctance. This cross-sectional study included responses of 855 Pakistani residents. Respondents’ knowledge of COVID-19 infection, intent of vaccination and barriers towards vaccine refusal were evaluated. Participants were categorized on the basis of knowledge score, risk of disease and other demographic characteristics. Descriptive statistics were used for calculating frequencies and percentages, means and Chi-square test was utilized for cross-tabulation. A multinomial logistic regression model was executed to identify the predictors of vaccination intention. Significance level was set at the p-value of ? 0.05. Prevalence of vaccine refusal was 40%. COVID-19 vaccine is not Halal, negative propaganda on social media against the vaccine, discouraging advice from social circle and clerics, concerns regarding efficacy, fear of immediate and late adverse reactions were the major barriers identified towards vaccine hesitancy. Around one-third of the study population did not consider COVID-19 as a serious disease and associate it with conspiracy theory. The mean score of participants towards COVID-19 knowledge was 5.5±1.6 (range: 0-9). Having a college degree, living in an urban area, working in a healthcare field and being in a higher risk category increases the chances of vaccine acceptability.