Active student participation is critical to the delivery of medicinal chemistry components of the pharmacy school curriculum. Carefully structured active learning strategies can promote student engagement while increasing course material application. Topic-based active learning assignments can be administered, where learners apply constructed knowledge and skills to complete assignments. The suspension of on-campus classes due to the COVID-19 pandemic prompted the development of innovative ways to deliver active learning assignments without using the school’s physical team rooms. To actively engage learners, the Zoom video teleconferencing platform with breakout rooms was used to conduct medicinal chemistry active learning assignments in a Pharmacotherapeutics IV: Endocrinology course. The students’ assignment scores showed no significant difference when assignments were conducted virtually using Zoom breakout rooms versus on campus, suggesting successful virtual administration of the assignments and students’ prompt adaptation to the new environment. The combination of Zoom-based lectures with actively facilitated Zoom breakout room assignments is an effective active learning strategy.

Background: The objective of this systematic review was to characterize the efficacy and safety of evening primrose (EP) for facilitation of parturition in peripartum persons. Methods: This search sought records related to the efficacy and safety of EP preparations to facilitate parturition. Eligibility criteria were primary literature with efficacy or safety outcomes reported; studied in peripartum persons; and available in English. Records were excluded if they were available as abstracts only. Data was synthesized by study characteristics, patient demographics, and outcomes. The RoB2 and ROBINS-I were used to assess risk of bias. Results: A total of 11 studies met inclusion criteria: seven randomized placebo-controlled trials, one randomized non placebo-controlled trial, one case study, one observational retrospective study, and one quasi-experimental cross-sectional study. Efficacy outcomes included Bishop scores and duration of labor during the different phases. Reported adverse events were generally mild and included increased blood pressure, decreased heart rate, pain, bleeding, nausea, and vomiting. Important risks of bias exist across the literature reviewed. Conclusion: The use of EP for parturition in peripartum individuals is not recommended. Further research is warranted before use during parturition or the peripartum period. Other: The authors deny conflicts of interest. The study was neither registered nor funded.

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