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Multilevel inverters are used in many industrial applications because of good power quality, minimum losses and less harmonics contents. Multilevel inverters require no series connected synchronized switching devices, transformer and complex filters. In this paper 10, 18, 24 diode clamped multi-level inverters (DCMLI) are implemented using trust region dog leg optimization method to find the optimized values of switching angles (θ). It decreases the total harmonic distortion (THD) of the output voltages and to reduce the complexity of external filter required. The multi-level inverters are implemented in MATLAB Simulation and results are compared in terms of harmonics, system complexity and efficiency.