ABSTRACT… Background: Lipid lowering therapy in documented Coronary artery disease is considered secondary prevention and lipid levels have significant influence on CAD Death rates. Objectives: To find out the frequency of dyslipidemia in patients of ischemic heart disease patients and to compare the results with international studies. Study Design: A descriptive case series study was carried out. Setting: The study was done in Medical Unit-II and CCU of Allied Hospital Faisalabad. For 6 months from 15march 2016 to 15 September 2016. Subjects: 50 patients diagnosed to have angina pectoris and ischemic heart disease patients were included. and all 50 Patients were on routine diet and were asked not to take anything overnight. Blood sample (5cc) was taken in all 50 patients with overnight fasting and blood sample were sent to Allied Hospital Laboratory immediately for analysis of (Triglycerides, total cholesterol, LDL and HDL). Reagents used were those of: "Merck Diagnostia Germany" Triglycerides were measured by ready to use reagent-using enzymatic splitting with lipoprotein lipase and quinoneimine as indicator. Total cholesterol, HDL and LDL were measured by "CHOD PAP METHOD" using ready to use reagents. Methods: Diagnosis was made on the basis of history, clinical examination and ECG findings. The history included chest pain, palpitation, sweating and shortness of breath. Ischemic heart disease patients'. ECG criteria were ST segment depression, T-wave flattening and inversion. All patients were subjected to fasting lipid profile. Results: Out of 50 patients, 30 were males and 20 were females. The frequency of dyslipidemia was 60% in patients of angina pectoris and ischemic heart disease patients. Triglycerides were elevated in 56 %. Male were 40% and females 16% and P value regarding gender distribution was 0.063; significant one indicating that there is a definitive relation between gender and hypertriglyceridemia. Total cholesterol was elevated in 20%. Males were 12% and females were 8%. And P value regarding sex distribution was 1.00. LDL was elevated in only 4%. HDL was also elevated in 4% of the cases. Conclusion: Present study concluded that dyslipidemia is common in angina pectoris and ischemic heart disease patients especially males and all patients of angina pectoris must be screened for dyslipidemia as early as possible and should be treated aggressively to minimize the risk of further complication of angina pectoris.
Background: Lipid lowering therapy in documented Coronary artery diseaseis considered secondary prevention and lipid levels have significant influence on CAD Deathrates. Objectives: To find out the frequency of dyslipidemia in patients of ischemic heart diseasepatients and to compare the results with international studies. Study Design: A descriptive caseseries study was carried out. Setting: The study was done in Medical Unit-II and CCU of AlliedHospital Faisalabad. For 6 months from 15march 2016 to 15 September 2016. Subjects: 50patients diagnosed to have angina pectoris and ischemic heart disease patients were included.and all 50 Patients were on routine diet and were asked not to take anything overnight. Bloodsample (5cc) was taken in all 50 patients with overnight fasting and blood sample were sent toAllied Hospital Laboratory immediately for analysis of (Triglycerides, total cholesterol, LDL andHDL). Reagents used were those of: “Merck Diagnostia Germany” Triglycerides were measuredby ready to use reagent-using enzymatic splitting with lipoprotein lipase and quinoneimine asindicator. Total cholesterol, HDL and LDL were measured by “CHOD PAP METHOD” using readyto use reagents. Methods: Diagnosis was made on the basis of history, clinical examination andECG findings. The history included chest pain, palpitation, sweating and shortness of breath.Ischemic heart disease patients’. ECG criteria were ST segment depression, T-wave flatteningand inversion. All patients were subjected to fasting lipid profile. Results: Out of 50 patients,30 were males and 20 were females. The frequency of dyslipidemia was 60% in patients ofangina pectoris and ischemic heart disease patients. Triglycerides were elevated in 56 %. Malewere 40% and females 16% and P value regarding gender distribution was 0.063; significantone indicating that there is a definitive relation between gender and hypertriglyceridemia. Totalcholesterol was elevated in 20%. Males were 12% and females were 8%. And P value regardingsex distribution was 1.00. LDL was elevated in only 4%. HDL was also elevated in 4% of thecases. Conclusion: Present study concluded that dyslipidemia is common in angina pectorisand ischemic heart disease patients especially males and all patients of angina pectoris must bescreened for dyslipidemia as early as possible and should be treated aggressively to minimizethe risk of further complication of angina pectoris.
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