ABSTRAKHospitalisasi dapat menimbulkan respon kecemasan pada anak usia prasekolah. Dampak kecemasan pada anak dapat mengganggu tumbuh kembang, proses penyembuhan, dan trauma. Terapi bermain origami merupakan salah satu intervensi yang dapat mengurangi kecemasan anak selama menjalani hospitalisasi. Tujuan penelitian ini untuk mengetahui pengaruh terapi bermain origami terhadap kecemasan anak usia prasekolah (3-6 tahun) yang menjalani hospitalisasi di RSUD Idaman Banjarbaru. Metode pada penelitian ini bersifat quasi eksperimental dengan rancangan penelitian pretest posttest non equivalent control group design. Pengambilan sampel menggunakan teknik consecutive sampling dengan sampel 30 anak usia prasekolah yang terbagi atas 15 anak kelompok intervensi dan 15 anak kelompok kontrol. Pengukuran kecemasan anak usia prasekolah menggunakan Preschool Anxiety Scale. Hasil analisis data menggunakan uji non parametrik Wilcoxon Signed Rank Test terdapat pengaruh terapi bermain origami terhadap kecemasan anak usia prasekolah (3-6 tahun) yang menjalani hospitalisasi di RSUD Idaman Banjarbaru(p-value 0,001).Kata-kata kunci: hospitalisasi, kecemasan, terapi bermain origami.ABSTARCTHospitalization can cause anxiety responses among preschool age children. Impact of children's anxiety when undergoing hospitalization may interfere with growth and development, healing process, and trauma. Origami therapy is one of the interventions to reduce anxiety among children during their hospitalization. The objective of this study was to measure the effectiveness of origami therapy on the anxiety among preschool children (3-6 years) during hospitalizatio Idaman Banjarbaru Public Hospital. The Method this study was quasi-experimental with nonequivalent pretest posttest control group design. The consecutive sampling technique was used in this study to select the samples of 30 preschool children, divided into 15 intervention group and 15 control group. Measurement of anxiety preschoolers using Preschool Anxiety Scale. The Results Analyzed using non-parametric test Wilcoxon Signed Rank Test, there was an effect of origami therapy on the anxiety preschool age children during Hospitalization at Idaman Banjarbaru Public Hospital (p-value 0.001).Keywords: anxiety, hospitalization, origami therapy.