Introduction: Postoperative cognitive dysfunction (POCD) following general anesthesia is frequent among geriatric patients worldwide. Neuroinflammation and neuronal injury have been associated with the incidence of POCD. Some biomarkers of brain damage including neuron-specific enolase (NSE) and S100B protein have been widely studied; however, their association with the incidence of POCD is still controversial. This study aimed to assess the correlation of serum NSE and S100B levels with the incidence of POCD among geriatric patients receiving general anesthesia. Methods: A prospective cohort study was conducted among geriatric patients receiving general anesthesia at Dr. Soetomo Hospital, Surabaya from July to October 2022. The Montreal Cognitive Assessment (MoCA) INA instrument was used to assess POCD, and enzyme-linked immunosorbent assay (ELISA) was used to quantify the levels of serum NSE and S100B. Spearman’s rank correlation was implemented to identify the correlation of MoCA INA scores with the levels of NSE and S100B. Mann-Whitney analysis was used to determine the association between NSE and S100B levels with the incidence of POCD. A p-value of ≤0.05 was considered statistically significant. Results: A total of 48 patients were enrolled in the study and 16.7% of them had POCD. Spearman’s correlation test suggested no significant correlation between MoCA INA score with serum NSE level (rs:-0.095; p=0.522) and S100B level (rs:-0.213; p=0.146). Mann-Whitney analysis indicated no significant difference in the NSE and S100B levels of patients with and without POCD (p=0.3470 and p=0.097, respectively). Conclusion: There was no significant association between NSE and S100B levels with the incidence of POCD among geriatric patients receiving general anesthesia during elective surgeries at Dr. Soetomo Hospital, Surabaya.

Rasulullah membekali Al-Quran dan Hadist kepada umat manusia sebagai pedoman hidup yang menuntun ke jalan yang baik dan benar. Al-Quran merupakan kitab suci yang mengandung ilmu yang wajib diberikan kepada anak terlebih dahulu. Memperkenalkan Al-Quran kepada anak harus dilakukan sejak berusia dini agar tumbuh sesuai dengan fitranya. Namun, sebelum Al-Quran dijadikan sebagai pedoman hidup maka langkah awal yang dilakukan adalah bagaimana membaca Al-Quran yang baik dan benar. Berdasarkan wawancara dengan Ketua Lembaga Pengambangan Tilahwatil Qur’an (LPTQ) kecamatan Pekanbaru Kota mengatakan persentase siswa Sekolah Dasar (SD), Madrasyah Diniyah Awaliyah (MDA) dan Taman Pendidikan Al-Quran (TPA) yang dapat membaca Al-Quran sampai ketingkat Tajwid hanya 40%. Penelitian ini bertujuan untuk meilhat faktor yang mempengaruhi terhadap kemampuan membaca Al-Quran siswa Sekolah Dasar (SD). Teknik yang digunakan pada penelitian ini yaitu teknik association rule algoritma FP-Growth. “Data yang digunakan merupakan data sekunder yang terdiri dari” 19 atribut dengan 214 record data. Hasil rule yang ditemukan dari penelitian ini sebanyak 163 rule “dengan menggunakan nilai minimum support” 30% dan “nilai minimum confidence” 50%. Hasil dari perhitungan ini hanya mengambil item makhroj, Panjang pendek dan tajwid. Dan menghasilkan rule dengan kombinasi 2 “itemset dengan nilai support dan confidence tertinggi adalah kombinasi jika Panjang Pendek buruk maka Makhroj Buruk dengan nilai support 66%, nilai confidence 99% dan nilai lift ratio” 1.47125

Currently the Family Computer store already has 3 branches and for sales matters it implements an offline and online system. But at this time the store still uses an offline system in terms of service matters such as: Warranty Claims, Service, and Current Status Checks.For this reason, research was carried out which aims to create a program to provide services online so that users when there are problems can provide easier access.This research was made after passing observations and interviews from local parties. Making this program uses the Android Studio application to create an Android application where almost everyone has an Android cellphone, and uses the Firebase Cloud Messagging feature from Google to provide service access to users so that users can monitor and get the latest information from the program without having to come to the store. or notify the admin at the store