Soil transmitted helminths are parasitic groups of worms that live in countries with subtropical or tropical climates. In humans, when exposed to parasitic eggs or larvae, they can cause infection. Stool examination is divided into qualitative and quantitative examination. Qualitative are direct examination, flotation, tape, deposition, and thick preparations. Kato-Katz and Stoll are quantitative. The purpose of this study was to compare the results of STH identification using the Formol Ether Sedimentation Method and ZnSO4 Solution Flotation with a total sample of 30 samples using purposive sampling. Data analysis with percentage tables and the Chi Square statistical correlation test The results of the analysis prove that the number of samples infected with soil transmitted Helminth with the Formol Ether Sedimentation Method and ZnSO4 solution flotation is the same. With p value = 0.850, which means there is no significant difference between Formol Ether Sedimentation and ZnSO4 solution flotation.

Hiperleptin mempengaruhi proses oksidasi enzim N-acetyldiphosphat (NADPH) yang berfungsi pada proses metabolisme dan reaksi redoks sehingga terjadi stres oksidatif. Peningkatan ROS menyebabkan aktifnya nuclear factor kappa beta (NFκβ) yang mengubah reaksi redoks di dalam sel melalui dimer p50 dan p65 yang bertranslokasi ke inti sel yang akan mempengaruhi gen promoter untuk mengekspresikan faktor kemotaksis yaitu monocyte chemoattractant protein-1 (MCP-1). Tujuan penelitian ini adalah melihat efektifitas quercetin pada penurunan ekspresi protein proinflamasi penyebab aterosklerosis. Penelitian ini merupakan eksperimental murni dengan menggunakan sampel kultur sel endotel manusia (HUVECs) yang diberi leptin 500ug/mL dan diinkubasi selama 6 jam yang selanjutnya diberi perlakuan quercetin dengan variasi dosis 0 µM, 50 µM, 125 µM dan 625 µM dan diamati aktivasi NF-κβ menggunakan metode immunofluorescence dan kadar MCP-1 menggunakan teknik ELISA. Hasil analisa data dengan menggunakan Tukey menunjukan adanya penurunan aktivasi NF-κβ yang signifikan setelah diinkubasi dengan quercetin dosis 125 µM (p<0,001) dan penurunan kadar MCP-1 sebesar 503,40±23,93324 (p<0,001) apabila dibandingkan dengan kontrol positif. Dosis optimal quercetin adalah perlakuan dengan dosis 125 µM karena memberikan pengaruh yang signifikan dalam menurunkan kadar MCP-1 dan penghambatan aktivasi NF-κβ. Dosis 625 µM hanya menghambat aktivasi NF-κβ tetapi tidak signifikan dalam menurunkan kadar MCP-1 (p=0,916). Peningkatan dosis quercetin menunjukkan korelasi yang signifikan dengan penurunan kadar MCP-1 (r=-0,498, p<0,001) dan penghambatan aktivasi NF-κβ (r=-0,803, p<0,001).

In the period of growth and development, adolescents need more nutrients. Adolescents face many health problems due to biological and psychological changes as well as malnutrition. Anemia is a common health problem. Riskesdas data in 2018, in Indonesia there is a prevalence of anemia of 48.9%. Cases of anemia often occur in the age group of 15-24 years and 25-34 years. This study aims to determine the state of anemia with a lean body mass index in adolescent girls at SMK Madani Turen, Malang Regency. The research design used is descriptive quantitative with a cross sectional approach and a total of 101 respondents. The samples obtained had a lean body mass index of 24 people (23.76%) and the majority were known not to be anemic, namely 17 people (70.83%) and those who had anemia were 7 people (29.16%). The p value of the Fisher's exact test is 0.000 if the p value is <0.05, which means Ho is rejected, it can be concluded that there is a relationship between body mass index and Hb levels in female students at SMK Madani Turen.