Background: Pancreatic cancer is one of the deadliest forms of cancer. The cancer grades define how aggressively the cancer will spread and give indication for doctors to make proper prognosis and treatment. The current method of pancreatic cancer grading, by means of manual examination of the cancerous tissue following a biopsy, is time consuming and often results in misdiagnosis and thus incorrect treatment. This paper presents an automated grading system for pancreatic cancer from pathology images developed by comparing deep learning models on two different pathological stains. Methods: A transfer-learning technique was adopted by testing the method on 14 different ImageNet pre-trained models. The models were fine-tuned to be trained with our dataset. Results: From the experiment, DenseNet models appeared to be the best at classifying the validation set with up to 95.61% accuracy in grading pancreatic cancer despite the small sample set. Conclusions: To the best of our knowledge, this is the first work in grading pancreatic cancer based on pathology images. Previous works have either focused only on detection (benign or malignant), or on radiology images (computerized tomography [CT], magnetic resonance imaging [MRI] etc.). The proposed system can be very useful to pathologists in facilitating an automated or semi-automated cancer grading system, which can address the problems found in manual grading.
Palm oil can grow in almost flexible topography. On flats, slopes, hilly, or undulating areas and whether on inland or reclaimed coastal areas. This makes the palm oil plantation environment unique with various soil types & surfaces. Each surface has a unique physical characteristic that directly influences the driving, handling, power efficiency, stability and safety of a robot. A mobile robot should have knowledge not limited to obstacles, but also the surface that the robot traverses to estimate wheel slippage and apply corrective measures. This paper discusses the harshness factors in palm oil plantation estates and the effects on wheel traction. We then present our review of several vibration-based surface classification techniques. Based on our survey, a combination of multimodal sensory for surface classification is more suitable to identify surfaces and terrain in palm oil plantations.
Background: Pancreatic cancer is one of the deadliest forms of cancer. The cancer grades define how aggressively the cancer will spread and give indication for doctors to make proper prognosis and treatment. The current method of pancreatic cancer grading, by means of manual examination of the cancerous tissue following a biopsy, is time consuming and often results in misdiagnosis and thus incorrect treatment. This paper presents an automated grading system for pancreatic cancer from pathology images developed by comparing deep learning models on two different pathological stains. Methods: A transfer-learning technique was adopted by testing the method on 14 different ImageNet pre-trained models. The models were fine-tuned to be trained with our dataset. Results: From the experiment, DenseNet models appeared to be the best at classifying the validation set with up to 95.61% accuracy in grading pancreatic cancer despite the small sample set. Conclusions: To the best of our knowledge, this is the first work in grading pancreatic cancer based on pathology images. Previous works have either focused only on detection (benign or malignant), or on radiology images (computerized tomography [CT], magnetic resonance imaging [MRI] etc.). The proposed system can be very useful to pathologists in facilitating an automated or semi-automated cancer grading system, which can address the problems found in manual grading.
Pancreatic cancer is one of the deadliest diseases which has taken millions of lives over the past 20 years. Due to challenges in grading pancreatic cancer, this study presents an automated cloud-based system, utilizing a convolutional neural network deep learning (DL) approach to classifying four classes of pancreatic cancer grade from pathology image into Normal, Grade I, Grade II, and Grade III. This cloud-based system, named PancreaSys, takes an input of high power field images from the web user interface, slices them into smaller patches, makes predictions, and stitches back the patches before returning the final result to the pathologist. Anvil and Google Colab are used as the backbone of the system to build a web user interface for deploying the DL model in the classification of the cancer grade. This work employs the transfer learning approach on a pre-trained DenseNet201 model with data augmentation to alleviate the small dataset’s challenges. A 5-fold cross-validation (CV) was employed to ensure all samples in a dataset were used to evaluate and mitigate selection bias during splitting the dataset into 80% training and 20% validation sets. The experiments were done on three different datasets (May Grunwald-Giemsa (MGG), hematoxylin and eosin (H&E), and a mixture of both, called the Mixed dataset) to observe the model performance on two different pathology stains (MGG and H&E). Promising performances are reported in predicting the pancreatic cancer grade from pathology images, with a mean f1-score of 0.88, 0.96, and 0.89 for the MGG, H&E, and Mixed datasets, respectively. The outcome from this research is expected to serve as a prognosis system for the pathologist in providing accurate grading for pancreatic cancer in pathological images.
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