StG patients had a greater degree of improvement in renal function, but with no correlation between degree of improvement in eGFR and delay in starting steroids, and similar eGFR values at final follow-up. PPI were the second commonest drug category among drug-induced cases.
Among haemodialysis patients in the United Kingdom, antibody-negative/RNA-positive HCV status is associated with newly acquired infection, rather than lack of antibody responses in chronic HCV infection. There is a significant risk of HCV infection associated with travel to resource-limited countries. Given that transaminase levels may be normal, HCV RNA testing is recommended in patients re-entering a dialysis unit following haemodialysis in settings where suboptimal infection control policies pose a risk of exposure to blood-borne viruses.
We describe a case of a young woman developing profound hypotension requiring inotropic support for 10 days following her second cadaveric renal transplant. Her central venous pressure was adequate, with no evidence of myocardial infarction, and an echocardiogram later showed normal left ventricular function. She had delayed graft function with gradual recovery of her renal functions. On day 45, she developed acute renal failure after removal of a ureteric stent. Ultrasound confirmed hydronephrosis, and a subsequent nephrostogram demonstrated filling defects, likely to be sloughed papillae, causing obstruction. She later had percutaneous removal of necrotic material from the ureter in order to establish free urinary flow with stability of her renal functions. The most likely explanation for papillary necrosis in our patient was profound hypotension postoperatively. We believe our patient's hypotension was secondary to dialysis‐associated cardiovascular autonomic dysfunction, with substantial improvement in blood pressure after a successful renal transplant.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.