sophageal variceal bleeding, though rare in children, remains a major cause of significant morbidity and mortality [1,2]. It may results in rapid depletion of the circulatory volume in children, as a result of their relatively small total blood volume [3]. Hence, effective resuscitation followed by prompt diagnosis, controlling of bleeding, and prevention of complications are important steps in the management of acute variceal bleeding [4]. In children, portal hypertension (PHT) from portal vein thrombosis (PVT) is the most common etiology of esophageal varices [1,5]. Risk factors for this include neonatal umbilical catheterization, omphalitis, neonatal sepsis with abdominal focus, and dehydration [6,7]. These factors result in PVT and subsequent disruption of blood flow throw the portal system leading to PHT [8]. The umbilical venous access (through umbilical catheterization) is one of the most commonly used routes for blood transfusion, intravenous fluids, and drug administration as well as parenteral nutrition in preterm neonates [9]. Catheter tip malposition, infection, and prolonged duration increase the risk of PVT [1]. We, therefore, report a case of bleeding esophageal varices in a 9-month-old infant who had umbilical catheterization