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Background: Prescribing errors are quite common and according to one estimate out of 100 patients admitted into UK hospitals 15 will have some form of prescribing error in their records. It is a general understanding that most of the time these errors are made due to lack of awareness. Severity of these errors can range from minor to major mistakes that can lead to fatal results. Materials and Methods: A simplified anonymous approach of identifying these errors and then using a step wise approach to educate the prescribers’ especially junior doctors can be quite fruitful in reducing these errors. Unfortunately there are not many studies or projects available to back our proposal however these seems a logical way forward and is exactly what we have shown in our study. Results: We performed a prospective snapshot study involving 100 inpatients to get baseline measurements. The errors and mistakes were identified and fed back to the junior doctors in an anonymous manner. Clear & legible writing, frequency of use, responsible consultant name, allergy box filled, VTE assessment, oxygen prescribing and labeling of medication discontinuation were the most common negligence identified. At the same time junior doctors were reminded of local prescription standards and guidelines which usually don’t form part of induction. Conclusion: Multiple deficient areas were identified during this audit like legible writing, dosage frequency, VTE prophylaxis and oxygen prescription. It was highlighted to junior doctors how important are these components as they play a key role in patient getting better after medical review. Above mentioned steps did improve prescription errors to an extent, but aim should be to achieve 100% results.  Repeated reminders are important in this case as that helps to improve practice and avoid clinical accidents.

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Background: At this instant, automated cell separators are used for the purification of platelets from healthy donors but the donor’s safety should not be overlooked. Hence, the present study aimed to compare the effect of platelet apheresis (via mega unit) on hematological indices of healthy donors. Methodology: In this cross-sectional study, 100 samples of healthy plateletpheresis or thrombopheresis donors were included. The pre and post plateletphresis hematological parameters were assessed. The total platelet count (PLT), hemoglobin (Hb), white blood cells count (WBCs), red blood cells count (RBCs), mean cell volume (MCV), mean cell hemoglobin (MCH) or mean corpuscular hemoglobin concentration (MHCH) were estimated through complete blood count (CBC) analysis and platelet apheresis was done by Mega unit Haemonetics MCS+9000 Cell Separator and 994- CFE. Results: After platelet apheresis procedure, a significant decrement in PLT value (p-value <0.001). And with that a remarkable difference was also observed in the haemoglobin, MCH and MCHC.  Conclusion: In conclusion, the hematological parameters significant decree among donors after the procedure of platelet aphresis but the revealed characteristics of thrombocytopenia and anemia were not found.