The paper described brief economic analysis and comparison of Turkish Airlines, Lufthansa Group and Air France – KLM. Throughout the economic and commercial development and with disappearance of boundaries between countries is rapidly changing air transport. The transportation and logistics investments and competition between companies and states rapidly increased. Thus, transportation modes developed and changed rapidly as a natural response to development itself. In the paper, we will practice the comparison of two major companies of European Air Freight: Turkish Airlines and Lufthansa.