To describe rational drug prescribing in general practice for elderly patients, using patients age, sex, encounters and the occurrence of some predefined inappropriate drug prescribing, according to Beer's criteria, drug-drug interaction of common OTC drugs and WHO essential drug list. A retrospective study on rational drug prescribing patterns in geriatric patient was carried out using prescriptions issued to the geriatric patients, 65 years and above, attending the outpatient and inpatient department of various hospitals and clinics of Hyderabad. Of the 150 prescriptions consecutively selected, Anti diabetics (142, 15.58%) were the most commonly prescribed medicines with metformin being the most prescribed anti diabetic. The medications prescribed by generic names were 92 (10.08%). 40% of medicines were prescribed from the WHO essential drug list. 17 (11.3%) prescriptions had one or more potentially inappropriate medicines from Beer's criteria and in 16 (10.6%) prescriptions drugdrug interactions were ascertained according to drug -drug interactions of common OTC drugs. The drug prescribing pattern among the elderly is still suboptimal. Appropriate interventions are needed for both health care providers and patients alike.

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