BACKGROUNDDiabetes mellitus is a leading public health problem with increasing incidence and long-term complications. Hyperuricemia is an independent risk factor for developing micro and macro vascular complications.
BACKGROUNDGlycosylated haemoglobin (HbA1c) is a parameter of glucose homeostasis and a marker for long -term glycaemic control. The aim of the study is to understand the pattern of dyslipidaemia among the Type 2 diabetic patients and to understand its association with Glycated haemoglobin (HBA1C).
1.BACKGROUND: Overweight and obesity are global public health problem with increasing prevalence worldwide1-3. It is a risk factor for
many metabolic and cardiovascular diseases including type 2 diabetes, hypertension, and dyslipidaemia etc4. Diabetic retinopathy (DR) is the
common micro vascular complication of diabetes mellitus (DM) and a leading cause of acquired blindness in adults. The aim of this study is nd
relationship between different BMI classes and DR development in type 2 diabetic patients.
2. AIMS AND OBJECTIVES:To determine the association of BMI and diabetic retinopathy and risk factors for DR
3. MATERIALS AND METHODS: A total of 206 type 2 diabetes patients from medicine ward of Swai man singh hospital and college Jaipur
[Rajasthan]. The subjects were classied into one of the three categories according to the BMI. (1).Normal BMI 18.5–24.9 kg/m2; (2).Overweight
BMI 25–29.9 kg/m2.(3).Obese BMI ≥30 kg/m2. Blood samples were collected after overnight fasting. Glycated haemoglobin value (HbA1c), total
cholesterol and triglycerides were measured. Complete eye examination included best corrected visual acuity (BCVA), slit lamp microscopy, and
fundus examination with binocular indirect ophthalmoscope and plus 20D lens after mydriasis with topically administrated 1% tropicamide and
5% phenylephrine eye drops was done. According to the DR status, patients were divided into two groups: group 1 (no retinopathy; N= 168), group
2 diabetic retinopathy; N= 38)
RESULT: Duration of type 2 diabetes was found longer with group 2 (9.6±4.5 years) as compare with group 1 (16.82±7.21 years). Association of
body mass index (BMI) of type 2 diabetic patients (n =206) with diabetic retinopathy, no correlation was found with mean BMI in group 1 (25.48 ±
2.4) and group 2 (27.21± 2.0)( P value <0.1). In our study were found signicant correlation of HbA1c with DR (p value <.01). Mean value of
HbA1c was higher in group 2 (8.41±.6) as compare with group 1 (7.01±.8). We found a signicant increase in total cholesterol (P <.01),
triglycerides (P< 0.05) with the diabetic retinopathy
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