<p class="abstract"><strong>Background:</strong> Despite its identification over 40 years ago, very few dermatologists are aware of the relevance of Frank’s sign as a cutaneous indicator of coronary artery disease. Aim was to find out the prevalence of Frank's sign among cardiac patients attending a tertiary care centre in Kanyakumari district.</p><p class="abstract"><strong>Methods:</strong> This was a cross-sectional case-control study involving 270 patients, out of which 200 patients with proven CAD (by angiography) and 70 patients without evidence of CAD of more than 40 years of age, in cardiac ward as well as patients attending Cardiology and dermatology OPD in Sree Mookambika Institute of Medical Sciences, kanyakumari during a period of 5 months from August 2020 to December 2020. The data compiled included age, gender, presence of CAD, presence of DELC, grade of DELC, and laterality. <strong></strong></p><p class="abstract"><strong>Results:</strong> DELC was present in 109 cases (40.3%) out of which 92 cases (34 %) had CAD and in 17 cases (6.3%) were without CAD, which was statistically significant (p&lt;0.05).</p><p class="abstract"><strong>Conclusions:</strong> There have been very few studies evaluating the frequency of DELC in South Indian patients with CAD. According to results of the present study, DELC was significantly associated with CAD. DELC was an important dermatological indicator of CAD with a moderately high specificity (75%) and positive predictive value (84%), but had a low sensitivity (46%) and negative predictive value (33%).  </p>

<p class="abstract"><strong>Background: </strong>Mask induced dermatitis is common among health care workers now because of the obligatory use of facemask for a longer period during COVID-19, the clinical features vary. Very few studies could be conducted due to the COVID induced constraints. Studies regarding reactions to face masks in health workers published to date are limited and hence we decided to do this study. The objective of this study was to find out the clinical presentations of mask induced dermatitis due to long term use of facemask on healthcare workers during COVID-19 pandemic.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study was conducted among 40 healthcare workers attend our OPD with face mask for 6 months. After getting informed written consent clinical evaluation was made by history and dermatologic examination.<strong></strong></p><p class="abstract"><strong>Results:</strong> Total 40 health care professionals between the age group of 21-50 years (17 females and 23 males) came to our OPD with complaints of itching and dryness with signs of erythema, scaling, papules for 6 months duration. Out of them, 15 (37.5%) patients had exacerbation of pre-existing dermatoses like atopic dermatitis, seborrheic dermatitis, chronic urticaria, acne. 10 patients (25%) had irritant contact dermatitis 7 patients (17.5%) had sweat-induced dermatitis, 4 patients (10%) had dermatitis due to sponge strip at the nasal bridge, 4 patients (10%) had dermatitis due to vehement use of ear loop involving retroauricular region.</p><p class="abstract"><strong>Conclusions:</strong> This study showed that wearing face masks results in the development and aggravation of other skin diseases due to various causes. Itch can induce scratching and thus lead to inappropriate use of face masks, which could compromise their function.</p>

<p class="abstract"><strong>Background: </strong>Coronary artery bypass grafting (CABG) is a cardiac surgical procedure in which the greater saphenous vein graft is most often used to bypass the narrowed coronary artery segments. The side effects of leg vein harvesting include a variety of cutaneous changes. We report the cutaneous effects at the saphenous vein harvesting sites in 32 patients who underwent CABG. To study the dermatoses occurring at the saphenous vein harvest site post CABG surgery.</p><p class="abstract"><strong>Methods: </strong>A prospective observational study on prevalence of saphenous vein harvesting site dermatoses in patients with CABG attending a tertiary care centre in Kanyakumari, for a period of 6 months from March 2021 to September 2021. The cutaneous changes on and around the saphenous vein (SV) graft donor site were noted in all patients.</p><p class="abstract"><strong>Results: </strong>A total of 200 patients underwent CABG during the period of study, out of which 32 patients developed dermatitis at the vein harvesting site. At the donor site, Pruritus was the most common symptom seen in 14 (44%) patients, followed by eczema in 11 (34%) patients, xerosis in 9 (28%), hyperpigmentation in 6 (20%), depigmentation in 2 (3%), anesthesia in 3 (10%), neuralgic pain in 3 (8%), burning sensation in 2 (6%), hypertrophic scar in 3 (10%), and infections in 3 (9%) patients.</p><p class="abstract"><strong>Conclusions:</strong> To minimize the donor site complications following CABG, we recommend proper cutaneous and vascular evaluations, identifying the best graft site, employing meticulous surgical technique, recognizing complications early, and starting treatment without delay.</p>

<p class="abstract"><strong>Background: </strong>Cutaneous metastasis from an internal malignancy is rare and usually occurs at the later stages. Cutaneous changes may also be the presenting feature of some underlying malignancies. To determine the frequency of cutaneous manifestations in cancer patients attending the Cancer centre of Sree Mookambika Institute of Medical Sciences, Kanyakumari.</p><p class="abstract"><strong>Methods:</strong> This was a prospective hospital-based study. 218 patients with malignancies involving various organs, attending the Cancer Centre of Sree Mookambika Institute of Medical Sciences, Kanyakumari, were recorded for a period of 6 months from October 2020 to February 2021. Approval from the Institutional research ethical committee was obtained.</p><p class="abstract"><strong>Results: </strong>In our study, the most common non-specific cutaneous manifestation was generalized pruritis, observed in 17.88% of the patients, followed by acquired ichthyosis in 12.38% of the patients, and herpes zoster in 11.46% of the patients. Specific cutaneous manifestations included cutaneous metastatic infiltrates, observed in 5.04% of the patients.</p><p class="abstract"><strong>Conclusions: </strong>Skin metastases may herald the recurrence of a malignancy after treatment and usually indicate a poor prognosis.</p>