In the recent decades, heterocyclic compounds six membered ring occupied a great deals of attention due to its wide and varied applications in medical, pharmaceutical, agricultural and industrial fields. Herein in this work fused pyrimidine as active type of the mentioning above have been successfully prepared by using supreme green chemistry techniques represented by solid phase one-pot muticomponent reaction (Biginille reaction) and microwave irradiation via mixing equimolar of thioamide (phenyl thiourea)-dimedone and substituted Benzaldehyde in presence of (2% mole) of boric acid and few drops of glacial acetic acid as selective acid catalyst at power (700 watt) for (1 min) to afford 7,7, dimethyl-1-phenyl-4-aryl-3,4,6,7,8–5H-quinazolin-2-thione-5-one (1-7) as pure products with high persentage.
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