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The aim of this study is to reveal the toxicity of design (landscape) plants in Bursa city parks. Landscape plants used in design works are especially evaluated in terms of aesthetics and functionality. However, design (landscape) plants can pose a risk to human and animal health due to the toxic organic compounds they contain. Within this scope, the design (landscape) plants in Hudavendigar City Park, Soganli Botanical Park, Resat Oyal Culture Park and Merinos City Park, which are used extensively by the city's people and which are described as city parks, were examined in terms of their toxic properties. The results showed that the taxa included in the major toxicity group were found at the highest rate in Resat Oyal Culture Park, followed by Merinos City Park, Soganli Botanical Park and Hudavendigar City Park, respectively. Nerium oleander, Taxus baccata, Eriobotrya japonica, Sophora japonica, Pittosporum tobira can be given as examples of taxa included in the major toxicity group. It was determined that design (landscape) plants with major toxicity are used less in city parks, which have been designed and opened to service recently. In landscape design works, it is significant for designers know the negative effects that plants can have on humans and animals due to toxic components other than their esthetic and functional properties. In this way, designs will be made to account for the toxic compounds, toxin conditions of plants, the degree of toxin and the toxic organs of the plants, and the present toxicity will be the least dangerous.