The aim of this report is to present a rare case of a Ghost cell odontogenic carcinoma (GCOC) of a 21-year-old man with review of the literature. The patient was treated surgically, and one of the surgical margins was involved, the patient received adjuvant radiotherapy for local control. Five months later, patient presented with infraorbital lesion which was proven histological to be GCOC. Radiological images, histological sections and clinical photographs are also presented. One year after the second surgery, the patient was tumor free. The only effective treatment modality was surgical removal.

Primary Oral malignant melanoma is a rare tumor with an indigent prognosis. This is a case report of 47-year-old Sudanese female diagnosed as Oral malignant melanoma of the mandible with an unusual pattern of growth and clinical presentation. Furthermore, a possibility of intraosseous origin is suggested.

Background Orbital infection related to mandibular third molar infection is extremely rare. Most of cases reported in literature are related to maxillary molar teeth. Odontogenic infections are not common causes of orbital abscess but it should always be put in consideration when dealing with orbital cellulitis and abscess. Case presentation This is a case of orbital abscess involving the left eye as consequence of lower left third molar infection in otherwise healthy 35-year-old black male patient. CT scan confirmed the unusual pathway of this space infection from the lower third molar and excluded any intracranial involvement. The abscess was drained immediately by intraoral incisions and the tooth was extracted. There was a dramatic improvement in a very short time with normal eye movement. Conclusion This case demonstrates one of the serious consequences of odontogenic infection which may lead to cavernous sinus thrombosis and blindness if not treated promptly.

The aim of this study was to describe the clinical and histological feature of intraosseous adenoid cystic carcinoma (IACC) and the treatment modalities with review of the literature. The authors report a case of intraosseous cystic carcinoma of the anterior mandible in an otherwise healthy 47-year-old patient along with a brief review of the literature. The main complaint was swelling and numbness of the right side of the lower lip. Clinically and radiologically, IACC is indistinguishable from benign odontogenic tumours and cyst. Routine histopathological examination and immunohistochemistry of incisional biopsy revealed adenoid cystic carcinoma. The lesion was surgically excised with surgical margins, which subsequently reconstructed using an iliac crest bone graft and followed by denture construction. On clinical and radiographic review 3 years post-operatively, the patient was well, free of symptoms with complete oral rehabilitation. The case demonstrates the features of IACC. Surgical excision with bone reconstruction and removable prosthetic replacement was effective in the treatment of this case. Regular follow-up was recommended. Clinical relevance Scientific rationale for studyTo report a very rare case of intraosseous adenoid cystic carcinoma, which clinically and radiologically resembled ameloblastoma. Principal findingsA painful intraosseous adenoid cystic carcinoma of the anterior mandible associated with unilateral lip paresthesia showing both lingual and buccal cortical plates expansion without perforation. Practical implicationsPain and numbness in a clinically apparent benign lesion should raise the suspicion of malignancy. bs_bs_banner

Oral verrucous carcinoma (OVC) and oral squamous cell carcinoma (OSCC) are tobacco associated neoplasms and sometimes it is impossible to distinguish between both clinically. This is a case report of OVC in snuff dipper and alcoholic 68 year-old male with massive mandibular destruction and multiple palpable lymph nodes where the clinical presentation was toward OSCC and the histopathological results revealed an OVC. A marginal mandible resection in OVC patient was performed with diagnostic selective neck dissection.