Although not statistically significant, this study showed a 100% protective effect of hyperbaric oxygen therapy against development of severe delayed neurological sequelae in patients with severe carbon monoxide poisoning. Further study with better study design is warranted. Loss of consciousness, low Glasgow Coma Scale score, intubation requirement, elevated troponin and higher creatine kinase levels were possible prognostic factors for development of delayed neurological sequelae in patients with severe carbon monoxide poisoning. A well-defined treatment protocol, appropriate follow-up duration and neuropsychiatric tests together with a hospital-based hyperbaric chamber are recommended for management of patients with severe carbon monoxide poisoning.

Different facets of hepatitis B infections are encountered in a renal unit. The viral antigens are implicated in the pathogenesis of some cases of glomerulonephritis. Hepatitis B surface (HBS) antigenaemia frequently persists in dialysis patients who contract the virus and presents a significant health hazard to the attendant staff. Persistent HBs antigenaemia does not jeopardise renal allograft survival. The effect of antiHBs antibodies is not clear. Transplantation can reactivate latent hepatitis B infections and render patients HBS antigen (HBSAg)-positive. Hepatic malignancies have been observed and increased patient mortality reported in HBSAg-positive renal allograft recipients. The effect of immunosuppression and maternal viral infection on the fetus is open to speculation.